Here’s a talk refuting the common misconception that complex traits are determined by few genes with large effect sizes.
For example you can’t upload your DNA to a service that says you have a “social anxiety gene”, it can say so but it’s false, you need a service that consider all of your genes, like Nebula with polygenic risk scores.
Blood pressure, extremely polygenic (genes that are statistically significant is colored dots above the red dotted line).
