Molecular pathways of Traditional Chinese medicine-derived compounds in

#1
1 Like
#2

There are a number of isolated phytonutrients that have powerful longevity effects in Chinese herbal medicine (and other herbal medicine systems).

A recent example of this is homoharringtonine:

1 Like
#3

Are there any human in vivo RCTs characterizing outcomes for these senolytics?

#4

I’m not sure but this is a drug that was used in humans for certain types of cancer so I imagine there would be a lot of human data.

#5

Glancing at the paper itself it seems not to make any reference to HDAC inhibition or AMPK activation although there is reference to AMPK in the citations.

1 Like
#6

The full article:

The representative herbs are on page 5. The usual suspects are there - astragalus, ganoderma lucidm (reishi mushroom), curcumin, kaempferol, etc.

1 Like