Metformin can slow the progression of age-related macular degeneration

There is no cure for dry AMD, though lifestyle modifications and supplements may help slow its development. Wet AMD can be treated with monthly injections into the eye to slow its progression, especially when it is diagnosed early. However, vision loss cannot be reversed once it has reached a certain point, so, researchers are still looking for more accessible and affordable treatments for all forms of AMD.

Since AMD is closely linked with aging, some researchers have turned their attention to metformin—a drug better known for treating type 2 diabetes—because of promising data on its overall anti-aging effects. Some studies have found that diabetic patients taking metformin have a lower incidence of age-related diseases such as cardiovascular disease, cancer, and cognitive decline compared to non-diabetic individuals or diabetic patients not on metformin. These results have led researchers to hypothesize that metformin may confer benefits beyond diabetes management.

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