ME-3 Lactobacillus Fermentum

#1

From ChatGPT:
• The original strain (Lactobacillus fermentum ME-3, DSM 14241) was deposited at DSMZ (Germany’s strain bank).
• Licensed companies (VF Bioscience in Europe) culture it under controlled lab conditions → freeze-dry it → encapsulate it.
• So unlike common yogurt cultures (which can be propagated locally), ME-3 is tightly held under patent/licensing agreements. You won’t find it just by buying generic L. fermentum.

I can no longer find the strain ME-3 anywhere. Must be a patent problem according to ChatGPT. Consumer Labs in their lipid section once favorably reviewed a product called Reg’Active ME -3 which contains this bacteria strain that lowers lipid levels. It was available on Amazon. Has been unavailable and off the market for a year now. It really lowered my lipid levels to normal. .
I take 5 mg rapamyacin weekly and the only side effect I’ve from this is dosage is elevated lipids. ME-3 worked like a charm.

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#2

I was buying Regactive with ME-3 on Amazon, but recently it became unavailable.

#4

(post deleted by author)

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#5

This is the brand that I know of, looks like they are just out of stock:

As an aside I did not notice any positive effects on this probiotic after using it for a few months.

I am a bit skeptical of the specialized strains. Yes this is the one that has been studied and yes it probably has higher overall antioxidant properties than normal L Fermentum. But what’s stopping you from buying bulk L Fermentum at Custom Probiotics or Bulk Probiotics at like 200b vs 8b in these capsules? Even if its’ a small fraction of the amount of antioxidant ability the dosage should make up the difference?

#6

I also used it for a few months and also didn’t notice anything good or bad.

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#7

It looks like ME-3 has a few extra unique mechanisms that distinguish it from just plain L Fermentum, in that it actually generates Glutathione vs recycling it (Lactobacillus fermentum ME-3: A Breakthrough in Glutathione Therapy - PMC)

It’s a shame because I have had a good response to other probiotics that produce compounds in the gut, namely C butyricum, the Miyarisan brand. I was very drawn to the idea that the Glutathione is produced where it needs to be, in the gut. Parkinson’s runs in my family and I was going to recommend this to my mom who has it if it helped. Maybe the 8bil dose is just too low?

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#8

Dr. Pelton is on this forum. Perhaps he can chime in on this.

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#9

For one small personal shipment, I basically had to:
Navigate the FDA Prior Notice system,
coordinate with FedEx International Clearance,
and pay multi-agency brokerage fee. Supplements are considered food when coming from Europe and are required to to have an extensive FDA form filled out. The seller didn’t file the form upfront so it was held by customs. It took me an afternoons work to fill out the form. it’s released now and on its way. Supplements coming from Europe are heavily regulated and taxed.

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#10

i used essential ME-3 for 5 months, one cap daily and just got my blood panel results and the glucose, lipids and triglycerides were much improved. No abnormal flagged results. I am sold on it. I still weigh the same as before and I and haven’t been exercising… I stopped rapa a month before the draw and all supplements a week ahead and fasted for the draw. I think it works for me. It’s available again in the US.