Excellent. Thanks
“ Our findings argue against what many people are already doing — using commercial products like quercetin or related compounds like fisetin that may show some senolytic properties," says senior author Sundeep Khosla, M.D., an endocrinologist at Mayo Clinic in Rochester, Minnesota. “They’re using them as anti-aging agents without knowing if they have high enough senescent cell numbers to benefit, or what dose or dosing regimen is needed to be effective yet safe.”
It’s good to have some closure here. Senolytics seem to be a therapy that is useful for people who have undergone accelerated aging or have a high senescent cells load. I might consider it around 65.
Can someone tell me how I’d go about testing for the amount of senescent cells in my body?
Actually more to this. Attached is the full write up of this Mayo Study.
Cut and pasted from this study: “We hypothesized that women with a high basal senescent cell burden would be more likely to respond to a senolytic intervention; thus, we selected women aged >60 years with a senescent cell burden based on p16 mRNA expression in peripheral blood T cells greater than the 95th percentile of young control women aged 22–31 years.”
My question to you is "how to I get this p16 mRNA expression tested?