Has anyone looked into the total (and dose-dependent) impact of this male birth control gel on key male hormones, including testosterone, 17-alpha estradiol and beta estradiol levels?
Seems like it might be interesting to look at…
NES/T is short for the two main ingredients it carries, nestorone and testosterone. Nestorone, also known as segesterone acetate, is a synthetic version of progesterone, a hormone that plays a major role in regulating pregnancy and other reproductive functions. Nestorone and similar drugs are already used as hormonal birth control for women. When it’s given to men, the drug lowers the levels of hormones in the testes responsible for male fertility, including testosterone, which then leads to low sperm counts. But it also lowers testosterone circulating in the blood, which can counterproductively reduce men’s sex drive, among other adverse effects. By reintroducing synthetic testosterone through the gel, the goal is to maintain stable hormone levels in men’s blood, ensuring temporary sterility and minimizing side effects.