M.E/CFS Rapamycin and Ketogenic diet

Hi
I recently started taking Rapamycin as it is now one of the drugs being researched as treatment for M.E. There has been quite a lot of anecdotal evidence that it is helping to reduce fatigue in people with M.E.
I have found that the maximum I can take is 2mgs once a week which has boosted my energy levels by about 30% and I generally feel less unwell.
But if I go above 2mgs the reverse happens.
My question is, could my clean keto diet be affecting the effectiveness of the Rapamycin.

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If you think your diet may be impacting the effects of Rapamycin, you could try an experiment of switching to a different diet and gauging if there are any changes.

Everyone has a unique biology and what may be good for you might not be good for others and vice versa.

So why not give it a try?

I’ve been doing Keto with Rapa for about 3 years. My keto diet is not as clean as yours, I eat veg and berries now, though I didn’t at the beginning. My biggest problem was cramps. I think keto and Rapa both make you low in potassium? I increased magnesium and use 1/2 potassium salt to fix that. Magnesium is very important. Attia takes a gram a day of slow mag.

I wonder about Iron too. I think Rapa can reduce Iron. If you’re low then lactoferrin is a great solution IMO. Copper helps Iron too.

Do you have more information on this?

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See this clinical study being initiated:

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