If you are in Australia, just go to any compounding pharmacist to get the right dose. I am planning to split the 50mg pills into 4 myself for now… LOL. At the very least I will have 10mg and the most i will have 12.5mg. All within my tolerance level. Has anyone thought about taking 25mg every alternate days?
when it comes to splitting tablets ive always wondered if the active drug distribution is equal throughout the pill it self, so splitting a 50mg pill into quarters would only give roughly 12.5mg per quarter only if the manufacturer made sure the drug distribution is equal, Im guessing thats why people dissolve it in water and dose that way
1 Like
I can tolerate 15mg easily… so no reason why 12.5mg is a problem. I want to cycle my dosage… maybe split the pill into 4 approx (12.5mg) … and have it for 2 days on and 2 days off… I hated the feeling I got from 20mg. But at 10-15mg, my psoraisis seemed to be a lot less. Plus now I started on ozempic… which has other benefits too… not to mention rapamycin every 2 weeks. I will take a break from rapamycin until my fingers start to hurt and it seems to solve that very quickly like within the first dose. I would like to know if anyone is familiar with cycling the supplement.
2 Likes
I’m starting using this brand tonight at 1.5mg. How have you gone with this brand?
After 4 weeks I had to stop LDN because of a reaction at 15mg. I took a week break. It took 3 days for the psoriasis to start creeping up. I restarted at 4.5mg and after 3 days the psoriasis started to clear up. I went back to to 10mg and didn’t go higher. 4 weeks lateri had another reaction. So I took 3 days off. And restarted at 4.5mg. next stop 9mg. See how long I’ll last again. Or maybe every 2 weeks I should take 3 days off? I didn’t think LDN can accumulate.
3 Likes
Can you explain to me what happened? How did it affect your sleep and what difference did swapping it to the morning make on your sleep?
been on 4.5 mg for 2 years now - its been a godsend for pain and sleep. Only negative is I don’t enjoy my Pinot Noir anymore
5 Likes
LDN was contributing to my insomnia, alongside ketotifen. Removing both of these massively improved my sleep.
3 Likes
Ditto @Paul, ditto!
Because I no longer love most food, I now need to add some naughtier things to my diet as incentive to eat.
Fortunately my diet was so OTT good that my idea of cheating isn’t too bad.
@AustraliaLongevity did you give the LDN a good long try before removing it? I only say this because it trashed my sleep for weeks and I planned to go off at the end of my one month trial, but then one day it all just flipped!
1 Like
I used it for months.
I had a very serious bout of insomnia for a while. It was weird because I was getting sleepy throughout the day but at night I would have adrenaline rushes while in bed and was wide awake. It soon dawned on me that something I was taking at night was causing this.
I eliminating ketotifen first and it helped but I still had trouble. I then eliminated LDN and my sleep got much better.
After that I got rid of magnesium and all supplements/medications except telmisartan and my sleep has been incredible. I don’t even take melatonin now, I think that was messing with my sleep.
I feel like telmisartan is quite good for sleep.
I used to be woken up so easily. I woke up this morning, sunlight coming through my window onto me. I honestly could have gone back to sleep right there but I needed to get up.
Additionally I dramatically lowered how much caffeine I was consuming. That did contribute a bit to insomnia but considering I was falling asleep during the day when the insomnia was the worst it couldn’t have been the caffeine, it had to be one of the medications/supplements I was taking.
2 Likes
I’m a lightweight with respect to ldn. I like it and use it nightly as part of my general protocol. Even at .25 mgs, it helped me decrease my etoh consumption. I titrated up very slowly to 1 mg but began getting short runs of heart palpitations for the first time. I cut out lots of other things; taurine, creatine, etc. they only stopped after I reduced back down to 0.5 mg.
I like to have more control over cravings, and am banking on other potential benefits, but I don’t really know what it is doing. I’m just hoping that it is doing something good for me.
2 Likes
Used it for a few months now (The LDN made by ‘healingpharma’ company), it is very subtle, I will switch out to ‘Lodonak’ next and see if I get the same experience. One thing I noticed was vivid dreams when I first started but after month two that faded. It is nice not having to split or titrate big 50mg doses so that saves a lot of time