Longevity protocol discussion

Hey,
Iong-time lurker here. Great stuff.

I recently stumbled upon an article you guys might be interested in.

Desmolysium - My Longevity Protocol

The guy, claiming to be an MD, uses a variety of longevity interventions.

Short summary:

  • diet, sleep, exercise (obviously)
  • 4mg rapamycin (has been for 4+ years)
  • 17-alpha-estradiol
  • allopurinol

He has also experimented with hit & run courses of senolytics (D&Q), SGLT-2 inhibitors, metformin, semaglutide, rosuvastatin, ezetimibe, and a host of other things.

He also claims to have been on rapamycin for 5 years, which is one of the longest experiences I have found online. My experience with rapamycin

What do you guys think of his approach generally and where does he go wrong?

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Not thinking there’s much here. He’s doing the basics and threw in a couple maybe helpful supplements and leaving out some others.
I think a lot of us have been on Rapa for 5 or more years.

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I found his take on teriparatide quite interesting.