Lab Mouse (Control) Cause of Death

I found this article that was quite interesting. It’s good to know the common mouse who is sacrificing itself for our sakes…

Conclusion

Cause-of-death assignment in preclinical rodent research suffers from a lack of a standardized approach and an understanding of the value that it can add to longevity and interventional studies. While assigning single cause of death may facilitate data analysis, defining and presenting data on comorbidities provides more information on associated underlying chronic conditions and health span in mouse models. Studies designed to assign comorbidities (contributory causes) in addition to cause of death may better translate to human aging and advance the field of “geroscience.”37

1 Like