Jack Ma-Backed Stem Cell Company Pollon Life Is Said to File for $300M Hong Kong IPO (Bloomberg)

@DeStrider what do you hear about this in Hong Kong? I can’t find a website for the company, which seems strange. (update, I think this might be the company’s china website: https://www.platinumlife.cn. )

Pollon Life, a Chinese maker of stem cell drugs, has filed confidentially for a Hong Kong initial public offering that could raise about $300 million or more, according to people familiar with the matter.

The company, backed by Alibaba Group Holding Ltd. founder Jack Ma’s Yunfeng Capital Co., is working with CCB International Holdings Ltd., China International Capital Corp. and UBS Group AG on the planned listing, the people said, asking not to be identified because the information is private.

Deliberations are ongoing and details such as the IPO size may change, the people said.

Pollon Life, CCBI and CICC didn’t respond to requests for comment. UBS declined to comment and a spokesperson for Yunfeng Capital, or YF Capital, couldn’t immediately comment.

Pollon Life, previously known as Platinum Life Excellence Biotech Co., developed the first stem cell drug — amimestrocel injection — to be approved for marketing in China at the start of the year.

Source: Jack Ma-Backed Stem Cell Company Pollon Life Is Said to File Confidentially for Hong Kong IPO (Bloomberg)

2 Likes

Here is an English language translation from CGPT5 of the company’s china website:

Here’s an English-language summary of the main content on the website of Platinum Life Excellence Biotech (Beijing) Co., Ltd. (Chinese: 铂生卓越生物科技(北京)有限公司). The site covers several sections: “About Us”, “Products & Services”, “Company News”, and “Contact / Careers”.

About Us
• The company was founded in 2010 and operates in the stem-cell biotech space. 
• Its lead product, Amimestrocel Injection (Chinese: 艾米迈托赛注射液), was conditionally approved by China’s regulator on January 2, 2025, making it the first approved stem-cell therapy in China. 
• The company claims to have built a large-scale production platform: a three-dimensional degradable microcarrier suspension culture system (automated, continuous, fully closed) for stem-cell drug manufacture, and a full lifecycle information-traceability system that tracks stem-cell products from donor to patient. 
• Their stated mission: “Born of love, acting by faith – to make stem-cell drugs that ordinary people can access and afford.” (rough translation of the Chinese) 
• Their vision: Become a first-class enterprise in the field of stem-cells. 
• Milestones listed:
• 2010: Company founded. 
• 2018: Submitted stem-cell clinical research report to the Chinese regulator (CDE) and got approval to begin Phase II clinical trials. 
• 2020-22: Initiated and completed a randomized double-blind multicenter Phase II trial. 
• 2023: Initiated key Phase III trial. 
• 2024: Completed Phase III trial; obtained China’s first stem-cell drug manufacturing licence. 
• 2025: Obtained China’s first “stem-cell new drug certificate” (i.e., approval for listing) for Amimestrocel Injection. 

Products & Services
• Their flagship product is Amimestrocel Injection. The website describes its indication: for patients (age 14 and above) with acute graft-versus-host disease (aGVHD) following hematopoietic stem-cell transplant, who are steroid-refractory (i.e., failed standard first-line treatment). 
• The mechanism description: The product uses human umbilical-cord-derived mesenchymal stem cells (hUC-MSC). Through both cell-to-cell contact and paracrine signalling (e.g., secreting prostaglandin E2 (PGE2), IL-6, indoleamine-2,3-dioxygenase (IDO)), it boosts regulatory T cells (Treg) and Th2 cells (anti-inflammatory) while suppressing Th1 and B cells (pro-inflammatory). The effect: reduced inflammation, tissue repair, lowered incidence and severity of acute GVHD, and opens up new therapeutic options in immune-related diseases. 
• There’s a customer service / pharmacovigilance hotline and email for drug safety/adverse-reaction reporting: Phone: 400-819-0099; Email: bszypv@platinumlife.cn and boshengzhuoyue@platinumlife.cn. 

Company News (“Dynamics”)
• Key news items include:
• On January 2, 2025: The product Amimestrocel Injection was conditionally approved by the regulator (National Medical Products Administration, NMPA) for listing. 
• June 28, 2024: Their new-drug application (NDA) for Amimestrocel Injection became the first stem-cell new-drug application in China to be accepted and placed on the “priority review” list (acceptance number: CXSS2400062). 
• May 31, 2024: The company received China’s first stem-cell drug manufacturing licence. 
• June 17, 2025: They published their corporate green performance (environmental) evaluation materials. 

Contact & Address
• Company name: Platinum Life Excellence Biotech (Beijing) Co., Ltd. (铂生卓越生物科技(北京)有限公司) 
• Address: Building 7, No. 8 Ruihe West 2nd Road, Beijing Economic & Technological Development Area (Beijing Economic-Technological Development Area), Beijing, China. 
• Customer service line: 400-819-0099. 
• Company email: boshengzhuoyue@platinumlife.cn
• Business registration: ICP licence number “京ICP备2022016208号”. 

Summary of Key Takeaways
• This company is a Chinese stem-cell biotech that claims to be the first in China to bring a stem-cell drug (Amimestrocel Injection) to market (for steroid-refractory aGVHD).
• They have built infrastructure for large-scale stem-cell drug manufacture (3D microcarrier suspension culture, automated/closed lines, traceability systems).
• They emphasise accessibility (“drugs for ordinary people to use and afford”) and aim to become a leading stem-cell enterprise.
• They maintain pharmacovigilance and customer-service infrastructure (hotline + email for adverse-reaction reporting).
• They are headquartered in Beijing, with full contact details listed.

1 Like

It sounds interesting and I’ll keep my eyes open for any info about them. However, I typically don’t get too excited about these things until I see some results and RCTs.

1 Like

Is “acute graft-versus-host disease (aGVHD) following a hematopoietic stem-cell transplant who don’t respond to steroids” simply the use case used to get this from trials to approved for human use to be prescribed and it can later expand to generalized longevity benefits?