Ivermectin for Dermatitis, Demodex mites and Rosacea

[Jonas]

Had a family member who encouraged me to try using Ivermectin for my skin “troubles”, ie, rash, eczema, and psoriasis.

I am happy to share that the results are incredible.

Anyone else? Reading on Reddit, doctors there are all horrified about the right-wing people using Ivermectin for various illness prevention. One wished them “depopulate” from that usage. So much “do no harm” for the medical profession.

Ivermectin OTC status

Ivermectin Mechanism and Pathway Map

the status of preclinical and clinical studies investigating ivermectin’s antitumor effects as of 2025:

[A_User]

What opinion will The Atlantic assign to me regarding the use of Ivermectin today? (I’m almost on the level of RapAdmin, who enjoys diversity of sources to the mix, like NPR and The Guardian, for a well-balanced view ).

How Ivermectin Became Right-Wing Aspirin

Conclusion: Not good.

But my own opinion is that I would need an evaluation with MR or RCT and preferably on hard endpoints, if there isn’t, maybe it takes up brain real estate for those that exist for the same condition(s).

[Jonas]

A few expensive medications work on similar pathways to Ivermectin.

[A_User]

What does it mean to “work similar pathways”, how much, for instance?

[RapAdmin]

for inflammatory skin conditions it seems the evidence is not too bad - but its not aspirin

6. Rosacea & Other Inflammatory Skin Conditions

Benefits:

• Topical ivermectin (e.g., Soolantra) is approved for rosacea.
• Anti-inflammatory and anti-parasitic effects (e.g., on Demodex mites).

Evidence Quality:

• High, based on RCTs and regulatory approval.

See details here from your friendly neighborhood ChatGPT instance:

in what therapeutic areas is ivermectin showing preliminary health benefits and what is the quality of the evidence in these areas?

ChatGPT response:

ChatGPT - Ivermectin Health Benefits Summary

[Jonas]

This Lunatic has found a few interesting papers and has beautiful skin with rosacea:

[A_User]

All preclinical studies that have little generalizability for human in-vivo use.
Drug development is difficult, takes a long time, costs a lot, and is very unlikely to succeed.