15 units of semaglutide I’m resistant to. 20 units of semaglutide and it can cause vomiting… this is accompanied with SOME loss of appetite, but there’s still some hunger that caused the vomiting…
[by unit i mean 1/10th of]
I traveled with semaglutide this time.
i remember semaglutide earlier this year made me vomit all the cilantro/parsley i ate the previous day (that was stockpiled up).
[now last night i ate 1 lb of almonds and 4 cans of carrots/tomatoes]
this time, it made me vomit vitamin water once, and then once again it made me vomit apples/kiwi I ate later that day (and with a lag time of like 2 hours).
if absolutely needed, I can at least use anti-emetics… I somehow suddenly gained weight after traveling to SF for tACS intensives…
I threw up bile last night [some time after controlled vomiting out a meal of fruit + almonds] but my host gave me this
I know I had an antiemetic that worked when I tried Ayahuasca. So the vomiting issue should be easily solveable, I now know exactly why I took a long break from this…
Henry kept talking about it as the elixir of life .
nce it.
In clinicaltrials of Ozempic and Wegovy, nausea was reported in:
15.8 percent of those taking a 0.5 milligram (mg) dose of semaglutide
If you were my patient, I’d usually look to switch to low dose tirzepatide. I suspect you’ve got a compounded semaglutide as it would be useful to know how many mg you tolerate, but don’t get weight loss with, and how many mg is not tolerated. Then it is easy to make recommendations in general of the equivalence. I see a good number of people not tolerate a pure GLP-1 and do better with tirzepatide, but also have had a number with the opposite experience. Some people won’t tolerate any of them, but it tirzepatide isn’t tolerated, move on to retatrutide … and if a no go … then a different strategy is needed.
semaglutide this time (20 units) made me vomit everything out first day, then made me sick with nausea/dizziness second day (no vomiting, and no eating til the end [that was on friday]), and then I started having some appetite third day, and now appetite almost back to normal…
Yeah, I should only take this at home, and just more aggressively Ubereats salads if getting too hungry
A use for Semaglutide (Ozempic) that might not depend on weight loss ~15-30% of patients with type 2 diabetes have peripheral artery disease (narrowing of arteries in the legs due to atherosclerosis) – it causes pain induced by walking In this phase 3 trial, Semaglutide improved walking distance and quality of life in patients with type 2 diabetes and peripheral artery disease Semaglutide improved blood flow to peripheral vessels (measured by ankle-brachial index) and there was very low correlation between weight loss and improvement to walking distance So the benefits of Semaglutide here might be independent of weight loss (reduced inflammation and improved function of the endothelial cells that line vessels) https://thelancet.com/journals/lancet/article/PIIS0140-6736(25)00509-4/abstract
