And they destroy so much of the environment, murder so many animals, and take up land that can be used for the housing crisis…
3 Likes
3rd day, very strong appetite suppression continues, I only need 1 meal a day
Food still tastes good when I eat it, even if you eat half as much, that’s still A LOT over the course of any interval of time over a few days
Less noisiness is good. It’s a reset button I need. Less rumination. Also less energy at some intervals of time until 6am
I think I did 0.7 mg. I can try 0.5 mg next time. I don’t need weight loss, I only need CR
There are anecdotes on reddit that semaglutide reduce addictions of all kinds.
1 Like
Even non chemical addictions?
A frined that uses it for two years stopped drinking alcohol while on Ozempic, she said that before alcohol drinks had a taste of more now she can’t stand the taste of beer or mouthfeel of vodka.
just don’t overeat, as food seems to digest really slowly and you can throw up undigested food hours later…
If you just need CR, 0,25-0,5 mg seems like a good idea. People I know that use it for that use that dose. Seems really popular among people I know.
I did feel fatigue today and yesterday but Adderall is enough to kill it.
I injected 1mg 2 days ago and it’s wonderful
Took a break bc of canagliflozin trials but God I ate way too much
Except I vomited (without nausea) four times yesterday, vomiting food I even ate over 24 hours ago. It just won’t pass through
This is first time I’ve ever vomited. Next time, smaller doses
Also 90.2 lbs now. I did hit 88 in 2021 several times and I was really happy this year. I’ve never really sad this year though so I need extra to prevent overeating
I’ve been 105 lbs most of the time the past 2 years
back to 93 lbs. I’ve never lost weight on SLG but I know it’s good for me because hunger/overeating drives me crazy and it’s nice to not have to spend as much time on eating.
i still have surprisingly high appetite on SLG
I lost some weight this year but it’s partly seasonal and partly canagliflozin
On semaglutide, I think there are windows of the day when my appetite loss weakens and that’s when I can pack in 1200 calories at once easy.
I’ve become semaglutide-resistant… (learned to eat over semaglutide). Maybe I will try somewhat higher doses (though I vomited on one meal when I did it)
It’s not urgent or anything, but it’s nice to be able to eat less b/c eating (or drinking) too much can really overwhelm my brain/make me unable to focus.
15 units of semaglutide I’m resistant to. 20 units of semaglutide and it can cause vomiting… this is accompanied with SOME loss of appetite, but there’s still some hunger that caused the vomiting…
[by unit i mean 1/10th of]
I traveled with semaglutide this time.
i remember semaglutide earlier this year made me vomit all the cilantro/parsley i ate the previous day (that was stockpiled up).
[now last night i ate 1 lb of almonds and 4 cans of carrots/tomatoes]
this time, it made me vomit vitamin water once, and then once again it made me vomit apples/kiwi I ate later that day (and with a lag time of like 2 hours).
if absolutely needed, I can at least use anti-emetics… I somehow suddenly gained weight after traveling to SF for tACS intensives…
I threw up bile last night [some time after controlled vomiting out a meal of fruit + almonds] but my host gave me this
I know I had an antiemetic that worked when I tried Ayahuasca. So the vomiting issue should be easily solveable, I now know exactly why I took a long break from this…
Henry kept talking about it as the elixir of life .
nce it.
In clinical trials of Ozempic and Wegovy, nausea was reported in:
- 15.8 percent of those taking a 0.5 milligram (mg) dose of semaglutide
- 20.3 percent of those taking a 1 mg dose
- 44 percent of those taking a 2.4 mg dose never
If you were my patient, I’d usually look to switch to low dose tirzepatide. I suspect you’ve got a compounded semaglutide as it would be useful to know how many mg you tolerate, but don’t get weight loss with, and how many mg is not tolerated. Then it is easy to make recommendations in general of the equivalence. I see a good number of people not tolerate a pure GLP-1 and do better with tirzepatide, but also have had a number with the opposite experience. Some people won’t tolerate any of them, but it tirzepatide isn’t tolerated, move on to retatrutide … and if a no go … then a different strategy is needed.
5 Likes
^yeah i should try that next.
semaglutide this time (20 units) made me vomit everything out first day, then made me sick with nausea/dizziness second day (no vomiting, and no eating til the end [that was on friday]), and then I started having some appetite third day, and now appetite almost back to normal…
Yeah, I should only take this at home, and just more aggressively Ubereats salads if getting too hungry
https://x.com/MariosGeorgakis/status/1875937614139977903
idk how to interpret, but i gained weight in SF and really need to lose it off. I’ll find a way as I always do…
https://x.com/cremieuxrecueil/status/1910755529267290199
https://x.com/DrSamuelBHume/status/1907068742917337161
- A use for Semaglutide (Ozempic) that might not depend on weight loss ~15-30% of patients with type 2 diabetes have peripheral artery disease (narrowing of arteries in the legs due to atherosclerosis) – it causes pain induced by walking In this phase 3 trial, Semaglutide improved walking distance and quality of life in patients with type 2 diabetes and peripheral artery disease Semaglutide improved blood flow to peripheral vessels (measured by ankle-brachial index) and there was very low correlation between weight loss and improvement to walking distance So the benefits of Semaglutide here might be independent of weight loss (reduced inflammation and improved function of the endothelial cells that line vessels) https://thelancet.com/journals/lancet/article/PIIS0140-6736(25)00509-4/abstract
·
4,715
1 Like
https://jamanetwork.com/journals/jamaneurology/fullarticle/2831975
Metastudy. Halves dementia. SGLT2 only 0.83 OR
1 Like
also, it doesnt decrease muscle mass more than other methods of weight loss
given ALL the recent news this year + antiemetic availability, if the ozempic pen has microplastics (though these are largely offset [even if not more than made up for] by appetite reduction), there is now no good reason to not take it
1 Like
Tirz seems to have less side effects and better positive effects than Sema. Reta is promising but still in clinical trials and has some possible concerning increases in resting heart rate which made me decide on Tirz personally.
2 Likes
Be careful with undereating while on GLP1 agonists. You need to intentionally increase your overall protein macronutrient portion in response to lower calories, and have a good overall resistance exercise routine to maintain muscle mass.
You also don’t need to starve yourself to lose weight, this will just cause muscle loss. GLP1s eliminate food noise and can help you reshape your diet to something much healthier, and they show promise at eliminating drug addictions. I think they can help people make smarter decisions overall.
Tirzepatide also has GIP which directly burns visceral fat, among other functions. This is why I prefer Tirz over Sema.
It’s important to think about injectable substances in terms of milligrams, not units. I like to write on the vial what 5 or 10 units = in terms of mg. (e.g. 5 units = 2mg)
1 Like