Is anyone part of All of Us Research Program? Is it anywhere comparable to UK Biobank?

I haven’t received anything interesting yet, and they didn’t ask for much blood nor did they ask for longitudinal measurements

Likely to be lactose intolerant - lol - this has always been good for me.

DNA marker*

Gene

Your result*

rs6754311

Near LCT

CC

Also I can’t taste some bitter compounds - this is why I can eat raw vegetables so easily.

We looked at a place in your DNA that influences if you can taste a bitter compound called phenylthiocarbamide, or PTC.2 While PTC itself does not exist in food, some vegetables contain a bitter compound similar to PTC.

  • People who can taste PTC can taste similar bitter compounds in vegetables like raw broccoli and brussels sprouts. About 75% of people are able to taste PTC and related compounds.3
  • People who can’t taste PTC don’t taste similar bitter compounds in food.

Bitter taste perception is also influenced by other genetic and non-genetic factors.

Scientific details

The TAS2R38 gene makes a bitter taste receptor, which is part of our taste buds. Bitter taste receptors interact with our food and send signals to our brain that get interpreted as flavor.

We analyzed your DNA for the presence of a genetic variant

that alters TAS2R38 to allow for the detection of the bitter taste associated with PTC and similar compounds.10

DNA marker*

Gene

Your result*

rs713598

TAS2R38

CC

*Each of your parents provides you with a nucleotide at this position, but we don’t know which parent gave you which nucleotide.

Also I have dry earwax - this also makes me less prone to body odor.

This is the program you’re talking about, correct?

https://www.researchallofus.org/frequently-asked-questions/

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medRxiv preprint doi: https://doi.org/10.1101/2024.03.08.24303967 is a recent preprint article where researchers analysed data in UK Biobank to find which substances are associated with longer living and which substances with shorter living.

Anybody has access to the list of substances they selected for research but even more a list of substances they threw out plus on which criterion: there still may be valuable substances they discarded. More so there are many medically used substances that are not used or allowed in UK.

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FYI the full title is : Association between prescription drugs and all-cause mortality risk in
the UK population.
First author: Jonas Morin

@RapAdmin maybe a few members in this community including me could check if there are substances not yet included in the million substances effort that have been found to have either positive or negative effect by crossreferencing those lists?
One of the issues will be to convert brand names to unique substance names. I could help with that one.
The mayor problem for me is to get access to those lists preferably in excel format.

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