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The whole epigenetic clock is probably complete nonsense. According to it, rapamycin has no effect at all.
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I don’t think DNA methylation is irrelevant, but I do think it is had to draw conclusions from.
I thought I would look up AC11, though:
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If you believe in that, you might as well stop exercising and start taking ketamine instead 
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We all know that Gastric Bypass is great for longevity. 
We can draw no conclusions from this small study, I would posit.
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I agree. But it’s small studies all the way down. How to make progress with imperfect information….that’s the thing to figure out. We should be careful about jumping to conclusions whether we like the outcome or not.
Hmmmm.
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what study is this? link?