Hmmmm… sure looks like the opportunity for another Agetron… skunkworks project. Lol
You ask … what about jail time - for illegal blood distribution?
Meh! I got an extra 20 years to spend thanks to rapa. Hahaha.
I can see it now in the jail yard… Tough tatted prisoner: Hey bud… I am in for distributing Meth. What about you?
Me: Student blood! They all slowly step away.
I think this has been discussed here before. I would give saline and albumin a shot if I didn’t think I had anything better.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764071/
From the paper above;
“In 2017, the Monterey, California-based start-up Ambrosia began selling transfusions of young plasma—the liquid component of blood—for $8,000 per liter, despite the lack of clinical trials showing this treatment was safe and effective in humans.”
It’s a great article, which I can’t say I completely understand, but it’s also a little self contradictory and it seems like (though they’re getting closer) these brilliant MD PhD’s don’t really know yet either.
This field is fun to watch, fascinating.
The Pursuit of Ignorance - Stuart Firestein
Looking for the black cat in the dark room.
It’s not available yet. At once point Fountain Life were planning on offering it, but it seems to have been taken off their website. https://www.fountainlife.com
Plasmapheresis is a treatment is FDA approved for certain conditions, so I’m sure you could find a clinic that would do the treatment, but I believe it’s prohibitively expensive in the states at the moment. it’s around 6k US per treatment. I think your best bet right now is to see if you can get on a trial here. https://www.lyfspn.com
Honestly, for all the hassle, the results are still only a fraction of what is gained by rapamycin or any of the other ITP drugs. And those are much easier on the wallet and psyche.
However, this is much more interesting to talk about in a macabre way…
We really need a little more objective science here. Dose and frequency data to home in on the minimum effective volume, and max time between each plasmaspheres. Also, without albumin as this will better mimic plasma donation and appears to be supported by 2020 Conboy data. Mean time I will continue monthly plasma (800 mls, ~25% of volume) and platelet donations (~275 mls plasma) and track blood work and aging markers. Eleven liters of plasma donated in 2022. I haven’t seen any obvious outward changes in my 68-year-old body and nothing has jumped out in bloodwork although liver function shows some improvement. Albumin levels bounce back in a few days. Will be looking to track some of the markers shown in the recent (August 2022) Conboy paper, DNA damage, CD4.CD8. etc. if available at Labcorp. My Levine PhenoAge is in low 50s over the last few blood panels but was good before starting donations, so can’t really say how much of an effect, if any, donations have had on this metric. I suppose I should stop donations for a few months and start over with good baseline blood work.
Yes - absolutely. I’m participating in a plasmapheresis clinical study right now that is workin on this issue. They are doing a 4 arm blinded clinical trials - with two 3 month (or now 4 months in my case because I didn’t make them in December) periods of two plasmapheresis sessions (each 3 hours long) in one week per month, for a total of 6 plasmapheresis sessions. They also have a 6 month arm. See details here: Plasmapheresis Startup Looking for Clinical Trial Participants SF Bay Area
Another interesting recent paper related to this topic:
Full Paper PDF Here:
Not sure if this has been posted already, but there are some interesting updates here.
http://www.atlantisclinic.com/anti-aging.html
“Young Plasma” Treatment Plans
The frequency and timing of treatments is individualized. Many patients come every 3 months for 7 units of young plasma. Some patients with dementia are treated monthly and take Rapamycin as well (which we can prescribe). If you are interested in a free telephone consultation about these treatments with Dr. Chipman, call the clinic and he will contact you. We need to know your blood type so we can order the correct plasma and we’ll need a copy of a lab report to verify.
* #### 1 Treatment of 7 units : $8000
4 Treatment Package of 7 units each : $27,000
1 Treatment “a la carte” : $1000 + $1000/unit
For more info, see the “Young Plasma” website : http://www.young-plasma.com
Yes, there is also a lot of good discussion in this Mitteldorf post.
