Increases in LDL from canagliflozin?

Results: Compared with placebo, canagliflozin 100 mg reduced SBP by 3.43 mmHg and DBP by 1.05 mmHg. Canagliflozin 100 mg increased LDL-C by 0.10mmol/l and HDL cholesterol (HDL-C) by 0.05 mmol/l. Compared with placebo, canagliflozin 300 mg reduced SBP by 4.75 mmHg and DBP by 1.69 mmHg. Canagliflozin 300 mg increased LDL-C by 0.16 mmol/l and HDL-C by 0.06 mmol/l

convert Total cholesterol, LDL and HDL from mg/dL to mmol/L, divide the value in mg/dL by 38.67. To convert from mmol/L to mg/dL, multiply the value in mmol/L by 38.67.

That’s 6 points…

Sample size? And, How large are the error bars?

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Here is the article if anyone has the full text:

6 mg/dl isn’t much.


What is the increase from rapa