What if combine acarbose and empagliflozine? Than you get acarbose’s bonuses from cutting the peaks, and bonuses to decreasing adverse effects of sglt1 inhibition of Cangliflozine, just strict sglt2 effects of flozines, beneficial for heart and so on. Theoretically speaking.
What about LDL levels of your wife? Methionine levels? And Leucine? And creatinine?
I hardly believe, that keto is any good. Cause it increase lipids, and certain aminoacids, and loads kidneys. Maybe short term is ok though…
Do you take it 50 before every meal, or just once a day? If with every meal - how many of them do you have per day?
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Hi All, wanted to re-mention something Functional folks probably know, certainly more well known prior to statins (when Family Drs actually where more then vax / pill pushers).
Taking Thyroid, NP/Armor will drop LDL / ApoB quite fast and not much thyroid sup is needed to see the drop.
Who are on statins? Alot of elderly. Who are likely clinically hypothroid? The elderly in the same way the elderly’s ALL hormones have dropped off some to near zero. I’ve seen not so old folks blood tests and shocking; no E, T and free T3 is way low.
Target (IMO) get free T3 to mid to high mid range. The preferred sup is NP thyroid, a full range desicated; T1, T2 T3, T4. To much re why levothroxin (just T4) is a bad idea at any age. But if it converts its typically younger folks. Older esp older women do not convert T4–>T3 and are suffering.
Also; IMO; as we age letting LDL rise >>125 or more is a good thing for immune health, joints, brain, nerves etc. I think its bad to suppress LDL. I’ll say ok to wanting to drop Apo-A/B below 90 via some mechanism. But please start with getting your thyroid tuned up, then the liver nutricals, anti inflammatories; ALA, berberine, boswalia, et al.
Along with thyroid I also tell friends to get their hormones tested. Nothing good happens to the body with low T, E, progesterone, lesser; DHEA, pregnenelone, now Klotho can be supplimented, albet expensively, See klotho off biolongevitylabs.com. I’m in a private health group anyone can join, that gets another form of klotho. See: TPC ARMY to join that group should you have an interest. You can preview on youtube by searching Alex Kikel TPC.
Best to all, curt
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I only take it before a meal with carbs, so probably only a couple times a week tbh. Most likely not enough to do much.
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TBH, I have a hard time imaging a meal without carbs) Glass of milk? Piece of cheese? Steak without anything?
UPD. started to read about ketodiet.)
How much NP Thyroid are you taking? I always get weird lab readings once I take any form of T3
HI Luke, Just mentioning, blood test first AM draw, fasted. Take thryoid in AM prior day.
Clinical practice for raising free T3, the only metric worth titrating for, as long as anti bodies are low, reverse T3 are low to mid range.
Maybe 70% of dosing is clinical (symptoms) not to the blood test, least what a good Functional folks will do. Ingnore free t3 being mid range if the patient is slugish and has weight to loose. Night time heart palps will be one indicator of too much. IMHO a night of heart palps like you get on too much NP aren’t a risk, just an indicator. And this is very very rare. Last summer I was titrating up, as is common in heat (reverse intuitive) another 20%.
I’m on 180 mg NP, my wife 160 split dosing. IMHO the half life of the desicated thyroid is long enough where I never felt a benefit from split dosing vs the risk of compliance failure in the evening dose.
Natural (anything) has the enterage (all components) benefits vs single component synthetic. My view is NP to a much lesser degree Armor (which may not even be available which IMHO is good news) is much more effective at addressing low thyroid function then synthetics even with multi dosed T3/day.
If you are not in the US, NP is hard to get. Then try Bovine desicated over the counter: Raw Desiccated Thyroid Sale | Thyroid Awareness Month
Anti aging systems shows desicated thyroid but no way for me to buy from the US. Maybe EU folks can buy there.
Unfortunately I have yet to find a work around to buy NP without a prescription. But any licensed practitioner should be convincable to write a prescription. If they support experimentation, get a prescription for more then you need in 60mg pills and be prepaired to pill cut to titrate.
A cheap full blood test is at: hellogoodlabs.com a full, everything test is just $200, draws at quest.
Good luck, curt
180mg of NP thyroid seems a little high, no? Did you have hashimotos or very elevated TSH beforehand?
I personally never noticed much of any increase in heart rate anytime I have taken T3/T4, let alone palpitations. My Free T3 is sub optimal at 2.8 but my TSH is 1.6 and FT4 is 1.4, so I never know if I should or shouldn’t stick with NP thyroid or a T4/T3 combo.
Hi Luke, Only my views and words from the folks I deal with. Ignore TSH, just dose to clinical symptoms, with an eye on free t3 and reverse t3. My ideal TSH is 0.5. Useless for guidance. Only free T3 [r_t3, anti bodies in the extreme] has signal when exogenously supplementing.
I bais toward the enterage effect from whole compounds:
https://www.google.com/search?client=opera&q=what+is+the+enterage+effect&sourceid=opera&ie=UTF-8&oe=UTF-8
So I’d only consider a desiccated thyroid source… Assuming its available even a bovine source. I suppose in some countries only synthetic T4/T3 is available, then its better then nothing.
Luke, why not buy some of the bovine desiccated above and experiment. Indicators are increasing or decreasing energy, increasing or decreasing LDL. Heart palps. Mainly folks supplement thyroid is to raise basile metabolism, loose weight, and increse energy.
FYI going hyper-throid endogenously or via supplimentation can drive you over the peak and the far side iinto hyper thyroidism can put you flat on the couch (in the extreme). It feels like too much coffee x 10.
Good luck, curt
Just curious what the problem is with Armour Thyroid. I’ve been using it for years and have also heard it’s going to get harder to find. What’s your problem with it?
Hi Bicep, I’m reporting what I hear/heard. When Armor was sold, the new owner, some 10 yr ago (??) the new formula was not as effective. With NP available no need to risk armor.
Get tested, what is your free T3, if ok then you are lucky. No risk getting a prescription for NP as a comparison. We are all lab rats, doing self experiments.
Good luck, curt