I wanted to measure if rapa was useful for my N of 1 and it does!
I took a TruDiagnostic test in February before stating rapa and another one in November.
Before rapa my immune system age was 10 years younger than the chronological age. Now, after 9 months of 6mg weekly rapamycin it’s 17 years younger. I didn’t really change anything else during that period except I added acarbose (50mg/meal) a few months ago. My glucose is still too high though.
My DunedinPACE of aging was 0.84 and is now 0.769. As a reference Brian Johnson current score is 0.69 which is better but I’m sure my slow_aging/cost ratio is incredibly better.
Basically almost all the markers have improved even though I’m 9 months older.
Even better, I’ve got the new OMICmAge report for both dates.
Rapamycin
No
Yes
Age
59.95
60.73
OMIC Age
52.78
53.56
Age Diff
7.17
7.17
Percentile
38.71%
17.98%
I find it very interesting and somewhat surprising that, even though the absolute age difference stays the same with my biological age being 7.17 years younger, there is a big difference in the percentile. Basically it seems that being 7.17 years younger is 2 times more common (38.71%) at 59.95 years old than at 60.73 (17.98%).
The detailed risk reduction for various diseases below is even more interesting.
Rapamycin
No
Yes
Death
-14.26%
-45.16%
Cancer
-7.17%
-23.67%
Stroke
-6.98%
-25.86%
Heart Disease
-6.95%
-27.71%
T2DM
-6.93%
-23.99%
COPD
-5.67%
-16.49%
Depression
-3.40%
-16.01%
Quite impressive I must say. Obviously it’s a N=1 experiment
