How to lower RDW, also what do you guys think about my stack and biomarkers? (n=1)

Age: 39
Height: 6’2/188cm
Weight: 145lbs/66kg
Diet: Mostly plant-based. OMAD

Supplements and medications:

GlyNAC (3g of each)
Taurine (3g)
astragalus extract (500mg)
EGCG (800mg)
Cranberry extract
Olive leaf extract
vitamin C 500mg
Dutasteride
astaxanthin (12mg)
Cats claw (500mg)
Magnesium malate
vitamin d 10,000IU
vitamin k2 100mcg
COQ10 150mg
Lithium 5mg (every other day)
Multivitamin
250mg DHA 500EPA fish oil
berberine 400mg
acarbose 50mg (before meal)
gotu kola 500mg
MSM 2g
Reishi extract 500mg
atorvastatin 20mg
high dose melatonin (200mg)
7mg rapamycin 1x a week
milk thistle 1g
hesperidin 1g
Spironolactone 50mg
b12 1000mcg (2x a week)

Results from last blood test:

WBC: 4.4 103/uL
RBC: 5.21 10
6/uL
Hemoglobin: 14.8 g/dL
Hematocrit: 45%
MCV: 86
MCH: 28.4
MCHC: 32.9
RDW: 13.1
Platelets: 190
Neutrophils: 69%
Lymphs: 19%
Monocytes: 8%
Eos: 3%
Basos: 1%
Neutrophils: 3.0 103/uL
Lymphs (Absolute): 0.8 10
3/uL
Monocytes(Absolute): 0.4
Eos (Absolute): 0.1
Baso (Absolute): 0.0
Immature Granulocytes: 0%
Immature Grans (Abs): 0.0
Glucose: 78
BUN: 15
Creatinine: 0.98
eGFR: 101
BUN/Creatinine Ratio: 15
Sodium: 142
Potassium: 4.3
Magnesium: 2.2
Chloride: 103
Carbon Dioxide, Total: 21
Calcium: 9.7
Protein, Total: 6.7
Albumin: 4.7
Globulin, Total: 2.0
Bilirubin, Total: “under 0.2”
Alkaline Phosphatase: 94
AST (SGOT): 26
ALT (SGPT): 27
Bilirubin, Direct: N/A (too low to detect apparently)
Triglycerides: 69
HDL Cholesterol: 43
VLDL Cholesterol Cal: 9
LDL: 47
Hemoglobin A1c: 5.0
TSH: 0.937
Iron Bind.Cap.(TIBC): 381 ug/dL
UIBC 274 ug/dL
Iron 107 ug/dL
Iron saturation: 28%
C-Reactive Protein, Quant: “under 1”

Blood test was about two and a half days after rapa dose.

I know i should have gotten hsCRP and not regular CRP, I asked my doctor for hsCRP and he did CRP anyway apparently.

My RDW is always high. Normal high, but still high. I know that ideal is 12-12.5. I also know that for epigenetic tests it has more weight than any of the other biomarkers I tested. It’s the most heavily weighed biomarker for Morgan Levine calculator (according to which my phenoage is 30.6, probably only because my fasting glucose is so low and albumin is high).

My ALP is always also double the ideal like this. Technically not outside the reference range but on the high end. Not sure what’s going on there.

I have given several AIs this info and it tells me to gain weight and get off of rapamycin. It also tells me to lower my melatonin dose to a standard dose of ~10mg. I think these LLMs are biased in favor of conventional medical literature, not more fringe, cutting edge protocols like we like. Caloric restriction and rapamycin are the most tried and true longevity protocols yet they seem to be against both in my case. AI doesn’t like my Lymphs but I think that’s just a common side effect of Rapamycin.

My mother died at 68 and father died at 74 both of cancer, and I have had one form of cancer in my 20s and have had several benign tumors so I really need to be aggressive with my protocol.

I’m open to any suggestions here. If there’s any other blood tests I really need let me know, I already know i needed hsCRP and not CRP though.

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