It’s a potential plasmalogen source
Kevin Perrott
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Plasmalogens are critical cell membrane components THAT YOU CAN’T GET FROM YOUR DIET as they are chemically reactive and don’t survive digestion when eaten! As we age, our liver slows down in their production. People who make the most plasmalogens in old age live the longest and avoid dementia.
Here’s another publication from a global leader in plasmalogen biology, Dr. Dayan Goodenowe, CEO of Prodrome Sciences, who is an amazing scientist and entrepreneur who seeks to help as many people as possible with his breakthrough insights.
Have a look at the biology and the science and ask yourself if plasmalogens deserve more attention from the aging research community. I think they do and so does the Alzheimer’s Association.
https://alz-journals.onlinelibrary.wiley.com/…/alz.12110
8 Comments
Mike Lustgarten, have you seen this report from Kevin? May need to add plasmalogens (sea squirts, mussels, and scallops) to the diet to reduce Alzheimer risk.
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Thanks Tony… however dietary plasmalogens don’t really make it into circulation through the digestion. The foods that contain signficant plasmalogens are often healthy in and of themselves, but in studies that use them as a source of plasmalogen, they have not been able to detect a significant rise in blood levels of plasmalogens. Prodrome Sciences however does manufacture a supplement which is converted into plasmalogen on digestion (and releases DHA in the process… a two-fer!)
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Mike, in addition to the liver, muscle peroxisomes can create plasmalogens in response to resistance training and restricted blood flow (blood flow moderation with “bands” like KAATSU can increase blood levels of plasmalogens. I’ve been working with the folks at KAATSU to study the effects of blood flow moderation on metabolism and plasmalogen secretion is just one of the biomarkers that go up in response to blood flow restriction.
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It’s always interesting to me how a ‘new’ (plasmalogens have been around for YEARS) idea has to fight for any kind of attention because everyone is so focused on the ones that they are already invested in… I guess I’m the one who’s invested in plasmalogens now… lol
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Kevin Perrott Thanks Kevin for the great feedback! That’s interesting that plasmalogens are not well absorbed in the blood from dietary intake. I wonder if sublingual under the tongue would work?
Oh and thanks for the insight in KAATSU training. I hav…
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Tony, not sure about the ECM but we will be testing for NO… which we are pretty sure is the case.
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I’m not sure about sublingual absorption of plasmalogens. The purification of plasmalogens from natural sources is very difficult because of their sensitivity. Regardless, there is a supplement out now that does provide plasmalogen that makes it through the digestion.
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how about shark alkylglycerols? https://med-life.ca/…/shark-liver-oil-supplementation…
Shark liver oil supplementation enriches endogenous plasmalogens and reduces markers of dyslipidaemia and inflammation — MED-LIFE DISCOVERIES
