How to estimate human equivalent doses from animal studies

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#1

I often see people reach incorrect conclusion about doses of supplements and drugs because they read some animal study and then incorrectly calculate how high of a dose a human would need to get the same effect.

The problem is rooted in the use of incorrect scaling factors between animals and humans and is common even among respected scientists. I have also seen this mistake in peer-reviewed published studies numerous times.

I wrote briefly about why this problem is so prevalent, and how to best estimate human equivelent doses. See here:

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#2

I thought this may be of interest
Dose Conversion Animals to Human_2025-10-11_160051.pdf (6.1 MB)

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#3

I think I’ve read this one before. It’s a good article. I should mention that the tables in it have scaling factors that are not fully accurate because the have a safety margin included. But like I mentioned in the article I wrote above these scaling factors are fine to use if one realizes that they include a safety margin.

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