How Exercise Helps Mice Fight Pancreatic Cancer

#1

Not rapamycin, but interesting wrt not dying of cancer. I would guess that proactively exercising (that is, when one is healthy) might help cause one to not get cancer in the first place.

https://www.the-scientist.com/news-opinion/how-exercise-helps-mice-fight-pancreatic-cancer-70134

the researchers found that aerobic exercise activated interleukin-15 (IL-15), a cytokine typically released by muscles during exercise, which triggers inflammation to fight pathogens. That activation mobilized a subset of CD8 T cells—immune cells that target and kill cancer cells—that carried an IL-15 receptor, ultimately allowing them to better infiltrate and engage with the tumor. The mice that exercised were found to have more of these CD8 T cells in and around their tumors.

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#2

Exercise mediates ALL the mortality pathways…cancer, CAD, neurodegenerative. By far, my #1 lifestyle intervention.

Exercise unleashes a MYRIAD of protective metabolites that impact every cell. There are likely many we don’t even know about.

#3

This is why it’s important not to flood your system with antioxidants and anti inflammatory agents just before and after exercise. You don’t want to negate the hormesis effects.

#4

Indeed, I take them first thing in the AM, workout late afternoon.