How do you find a wide diversity of plants+fungi+protists to eat from, esp if you have limited time?

What are ways to easily get the wide diversity?

It helps reduce Glycanage and increases microbial diversity
Presumably, eating from a diversity of ethnic cuisines helps. Also spice racks (mixed no-salt seasoning}

I would go after a wide range of classes of plants. So gingko punches WAY above its weight, plus brown seaweed, plus …

beets (betaleins), some cannabis (they have crazy metabolite diversity), Blue Butterfly Pea flowers

https://www.amazon.com/Om-Organic-Mushroom-Nutrition-Botanicals/dp/B086CL5FN3

https://www.pnas.org/doi/full/10.1073/pnas.2111321118

https://www.sciencedirect.com/science/article/pii/S1360138518302115

tiger nuts… FERMENTED FOODS, like

https://www.amazon.com/Art-Fermentation-Depth-Exploration-Essential/dp/160358286X/

https://www.amazon.com/Future-Fungi-Feed-World-anglais/dp/1760761605/

look up john de la parra

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Lots of herbs and spices. Plant powders: turmeric, garlic, moringa, pea protein, onion, . Variety of nuts.

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Considering the spatial disparity in metabolites between leaf and stem components, the levels of branch chain amino acids (BCAA) (isoleucine, leucine, valine), aromatic amino acids (AAA) (phenylalanine, tyrosine), phenylpropanoids (cinnamic acid, caffeic acid, ferulic acid, shikimic acid), sugar alcohols (xylitol, myo-inositol, meso-erythritol), and glycerol derivatives (glycerol, glyceryl-glyceryl) were relatively higher in leaves than in stem extracts. Branch chain amino acids cannot be synthesized by animals; however, plants can synthesize these amino acids de novo and thus serve as an important source of these compounds in the human diet [24]. In plants, isoleucine, leucine, and valine share common BCAA-hydrolyzing enzymes in their biosynthetic pathways. Accumulation of free amino acids plays an important role in plant stress tolerance, and these can act as osmolytes under certain abiotic stress conditions [25]. Similarly, phenylpropanoids are key components with antioxidant functions that ameliorate high intensity light-stress mediated damage in leaves [26]. On the contrary, the levels of fatty acids (oleic acid, stearic acid, palmitic acid, and linolenic acid) and amino acids (proline, lysine, and arginine) were relatively higher in leaves compared to stem extracts. Oleic and linolenic acid derivatives partially regulate plant development, seed colonization, and defense responses to pathogens through various mechanisms [27, 28]. Notably, the relative abundances of chlorogenic acid and the majority of flavonoids (dihydrokaempferol, quercetin, quercetin derivatives, and myricetin derivatives) were higher in leaves, while kaempferol glucoside and pinocembrin were more abundant in stems. The higher abundance of flavonoids in leaves might be attributed to their local biosynthesis as well as their active translocation from other plant organs at different stages of development [29].

Generally, similar antioxidant activity levels were observed in the same genus groups, but the species belonging to the genera Alnus displayed significantly different antioxidant levels. These results suggest that the differences in chemical compositions among species belonging to the same genus may be expressed in terms of their varying chemotaxonomy and associated bioactivities. In the present study, multivariate analyses indicated distinct metabolite profiles for plant extracts according to different plant families and spatial parts. Hence, the chemotaxonomic hierarchy of plants depends on their biosynthetic relatedness to synthesize corresponding metabolite pools [30].

We observed that aceroside VIII, catechin, and quercetin derivatives were positively correlated with DPPH antioxidant phenotypes, whereas eriodictyol was associated with tyrosinase inhibition effects. According to recent studies, aceroside VIII is an acerogenin derivative with significant antioxidant activities [31]. Ellagic acid is structurally a phenol antioxidant that exhibits significant free radical scavenging activity. It also promotes the activity of three antioxidant enzymes, namely superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPX), which are altered under various physiological states involving free radical attack [32]. The roles of mannitol as an osmo-protectant as well as free radical scavenger that influences the activities of antioxidant enzymes including SOD, CAT, glutathione reductase (GR), peroxidase (POX), and ascorbate peroxidase (APX) have also been established [33]. Previously, Iacopini et al. described catechin, epicatechin, and quercetin as phenolic compounds that can independently or synergistically exhibit DPPH radical activities [34]. However, in the present study, eriodictyol and caffeic acid were linked to tyrosinase inhibition and total flavonoid content assays, respectively. Notably, eriodictyol is a flavonoid that can inhibit melanogenesis [35].

japonica…

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As a Western-trained physician, I had never heard of amla, which is dried, powdered Indian gooseberry fruit. I was surprised to find more than seven hundred articles on it in the medical literature and even more surprised to find papers with titles like “Amla, a Wonder Berry in the Treatment and Prevention of Cancer.” Arguably the most important plant in Ayurvedic medicine, amla is used traditionally for everything from a hair tonic to a snake venom neutralizer.6913 I eat it because it’s apparently the single most antioxidant-packed whole food on Earth.6914 See what four cents’ worth can do to the antioxidant power of a smoothie in see.nf/breakfast.
In the Ayurvedic lexicon, amla is considered “the best medicine to increase the lifespan”6915 and a “potent aphrodisiac,” but the evidence

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How do you avoid polypharmacy from eating so many plants with active compounds?

Those randomized to eat fourteen servings of fruits and vegetables a day for even just two weeks show a reduction in oxidative DNA damage compared to those randomized to eat only four servings a day,7088 but what about a study in which the number of servings is held constant and you just increase the diversity of the produce? That’s exactly what a group of researchers in Colorado did.
Both diets had the same number of daily servings (eight to ten), but the high botanical diversity diet included fruits and vegetables from eighteen different families versus emphasizing just five in the low diversity diet. Only those randomized to the high diversity diet experienced a significant reduction in DNA damage.7089 The researchers concluded that “smaller amounts of many phytochemicals may have greater potential to exert beneficial effects than larger amounts of fewer phytochemicals.” Observational studies have also found that fruit and vegetable variety is associated with lower inflammation7090 and better cognition7091—again, independent of quantity. Does this mixing and matching of a variety of plant foods actually translate into a concrete difference for patients?
Check out see.nf/foodcombining for a wild experiment involving secretly giving cancer patients a combination of a fruit, a vegetable, a spice, and a leaf—about one one-hundredth of a pomegranate, less than one floret of broccoli, less than an eighth of a teaspoon of turmeric, and about a sixth of a tea bag’s worth of green tea a day, hidden in capsules and randomized against placebo. Surely such tiny amounts couldn’t affect the progression of cancer, right? Wrong.7092 As I show in the video, the cancer was significantly slowed down.

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Maybe I’m missing something. Why do you need a wide diversity? Don’t some of the blue zone diets lack diversity?

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@KarlT

the American Gut Project
American Gut: an Open Platform for Citizen Science Microbiome Research - PMC

Instead, eating a diverse range of plants through an abundance mindset is the only rule Dr. Megan Rossi, author of How To Eat More Plants and Love your Gut, and a practicing dietitian and nutritionist, promotes.

“We can control the health of our gut microbiome, and the key predictor of that is diversifying your plants,” she tells Fortune.

In short, the more variety of plants you eat, the better. While it may seem ambitious, Rossi recommends aiming for 30 different plants a week from the super six: whole grains (think: quinoa, rolled oats, and sourdough bread), nuts and seeds (walnuts, pistachios, and pecans), vegetables, fruits, legumes (think: beans), and herbs and spices (cumin, cinnamon, and paprika).

“There’s none of the cutting out you may see with other eating plans,” Rossi writes in her book How To Eat More Plants. “This approach is enriching, not restricting; inclusive, not exclusive. More plants, more variety, more fiber, more flavor. I call it the Diversity Diet.”

Her examples still suck though, they’re mostly western foods and too much high-calorie grains

(and everything on that channel)

these are three separate questions, let me take them in order but flag where they connect.


international travel and microbiome diversity

probably yes but with important caveats about what kind of diversity and how durable it is.

the mechanism is straightforward: different regions have different soil microbiomes, fermented food traditions, water microbiota, and environmental exposures. you’re getting microbial inoculation through food, surfaces, air, even soil contact that your home environment doesn’t provide. studies on traditional populations vs. urban westernized ones show substantially higher gut microbiome alpha-diversity in the former, and the difference is at least partly attributed to environmental microbial exposure.

but the durability question is real. without ongoing dietary substrate to support the new organisms, transient colonizers probably don’t establish. you need the fiber/polyphenol substrate to maintain what travel inoculates. otherwise your existing microbial community outcompetes the newcomers within weeks of returning home.

highest yield travel destinations for this purpose are probably rural agricultural settings in tropical regions — not urban hotels where you’re eating sanitized Western-adjacent food the whole time.


best kind of tea / eating leaves

“best” depends on what axis but for polyphenol diversity and concentration:

shade-grown matcha is probably the most concentrated single-source polyphenol delivery available in common foods — you’re consuming the whole leaf, not an infusion. EGCG content is substantially higher than brewed green tea. the “eating leaves” instinct is exactly right here — brewing discards a large fraction of what’s in the leaf.

but I’d push back gently on optimizing for a single “best” tea. the polyphenol profiles are genuinely different:

  • green/matcha: catechins, EGCG dominant
  • oolong: partially oxidized, theaflavins beginning to form, different profile
  • pu-erh: fermented, contains compounds from microbial transformation that aren’t in any unfermented tea, genuinely distinct category
  • white tea: minimal processing, different catechin ratios

eating leaves broadly: yes for matcha, yes for dried herbs. most tea leaves from loose leaf teas are technically edible but the texture and tannin load makes it unpleasant at scale. culinary use of tea leaves (Japanese tea leaf rice, some Burmese cuisines literally eat fermented tea leaves as a salad — lahpet) is real and probably underexplored.


plant family diversity — the real question

yes, this is probably one of the most underrated dietary principles and you’re right that it’s almost impossible to pursue through normal restaurants.

the logic: different plant families produce different secondary metabolite classes because they evolved different chemical defense strategies. you’re not just getting macronutrient diversity, you’re getting exposure to genuinely different polyphenol scaffolds, alkaloids, terpenoids, glucosinolates, iridoids — compounds that interact with different receptors, enzymes, and microbial populations.

brassica dominance in “healthy eating” culture is a real problem. you can eat an extremely “healthy” diet that’s essentially all apiaceae and brassicaceae with some asteraceae (lettuce, artichokes), and you’re missing huge swaths of phytochemical space.

your specific examples:

olive leaves — oleuropein content is actually higher in leaves than fruit or oil. genuinely difficult to source but olive leaf extract is standardized and real. eating actual leaves is possible (they’re used in some Mediterranean folk traditions) but tough and bitter.

turmeric root — fresh root is substantially better than powder for curcumin content and the accompanying essential oils that affect bioavailability. available in many Asian grocery stores, underused.

ginkgo — the leaves contain ginkgolides and bilobalide, genuinely unusual terpenoid structures not found in many other plants. the seeds are edible (used in Japanese cuisine) but contain 4-O-methylpyridoxine which is actually toxic at high doses, so seeds are not the route. leaf extract is the practical form.

ginseng — ginsenosides are a family of triterpene saponins with genuinely interesting pharmacology. the diversity within ginsenosides (Rb1, Rg1, Rd etc.) means different preparations hit different targets.

magnolia bark — honokiol and magnolol are unusual neolignans with genuinely interesting GABA-A modulation and mitochondrial effects. not really a food though, more supplement territory.

the sustainability flag you raised is real

ginkgo: trees are extremely common as urban street trees. leaves are free and widely available in autumn. this is probably the most sustainable exotic plant on your list.

turmeric: highly sustainable, easy to grow, cheap fresh at Asian grocery stores.

olive leaves: if you have access to olive trees, leaves are a pruning byproduct. otherwise olive leaf tea is a real product.

ginseng: genuinely unsustainable if wild-harvested. cultivated is fine but the quality differential is real.

magnolia bark: sustainability concerns are real, various Magnolia species are threatened by bark harvesting pressure.

the restaurant problem

you’re right and it’s frustrating. the narrow vegetable repertoire of even “adventurous” restaurants is mostly:

brassicaceae (broccoli, cauliflower, kale, cabbage), apiaceae (carrot, celery, parsley), asteraceae (lettuce, artichoke), solanaceae (tomato, pepper, eggplant), cucurbitaceae (cucumber, zucchini), amaranthaceae (spinach, beet), fabaceae (beans, peas)

that’s essentially the entire Western vegetable repertoire and it’s maybe 7 families.

the places that break this pattern:

Indian restaurants come closest — curry leaves (Rutaceae), fenugreek, bitter melon, drumstick/moringa, various things outside the standard Western set. a good South Indian vegetarian restaurant is probably the highest plant family diversity per meal you can get in the US without specifically seeking it out.

Ethiopian food is underrated for this — teff (Poaceae but an unusual one), berbere spice diversity, various leaves.

Sichuan/Yunnan Chinese cuisine uses genuinely unusual plant parts — wood ear fungus, various mountain vegetables, Sichuan pepper (Rutaceae, completely different from black pepper).

Japanese kaiseki theoretically hits high diversity but in practice often defaults to the same narrow set with elegant preparation.

multi-hypothesis on whether the diversity itself matters or if it’s the specific compounds

H1 — plant family diversity is a useful proxy heuristic but the actual variable is specific compound classes (very likely, ~0.7): you want honokiol, oleuropein, ginsenosides etc. specifically. diversity is a good way to ensure you’re hitting them but it’s the compounds doing the work, not the diversity per se.

H2 — diversity itself matters through microbiome substrate diversity (plausible, ~0.5): different polyphenol scaffolds feed different microbial populations. the microbiome benefit might require genuine structural diversity that you can’t replicate by taking isolated extracts of each compound. the whole food matrix matters.

H3 — the bioavailability of most of these compounds from food sources is low enough that the distinction between eating olive leaves and taking standardized oleuropein extract is smaller than it seems (plausible, ~0.4): curcumin bioavailability from fresh turmeric is notoriously low. some of these exotic plants might be better pursued as extracts than foods.

H1 and H2 aren’t mutually exclusive — probably both true at different levels of analysis.

https://claude.ai/share/9f807ca0-bdc1-4480-8445-bd4a8e13bd96