How Anti-Aging Hackers May Advance Serious Science (Worth)

The author is a little off on his facts (rapamycin extends life up to around 25% in animal studies, not 15% as he states), but generally he gets the idea of what is going on. As always, Matt K. is on the ball :wink:

The quest for immortality, or at least delayed mortality, is in full swing, with billions going into antiaging tech such as stem cell and genetic therapies. But there are also several cheap, accessible venues for people who want to take a crack at extending their lives. They include off-label use of generic drugs such as diabetes med metformin and immune-system suppressant rapamycin. Studies in mice indicate that rapamycin could extend lifespan up to about 15%. Some preliminary data in humans indicate that the rapamycin may help slow or even reverse some aspects of aging on the cellular level. However, there are also signs of potential side effects affecting muscle and the immune system.

Suh isn’t sure about future informal studies, though. “You have to do the right, randomized, double-blinded clinical trials to evaluate the efficacy of the drug and on the outcome,” she says.
Kaeberlein doesn’t disagree, but he does see utility in more crowdsourcing, on a larger scale. “You could imagine somebody setting up a website and saying, ‘Come put your data in here,’” he says.

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