New miracle supplement found to boost memory and muscle strength in old age
http://www.gbnews.com/health/supplemements-hmb-memory-muscle-strength
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Not really “new” but that does help with the social media clicks a news site needs to stay alive.
1 to 3gm’s per day of HMB is typically used for muscle building, not sure about dosing for cognitive, it might be the same dose level.
I’ve played with it over the years, first tried it in 2018, taste is disgusting LoL! so don’t use it in a shake 
The higher you go, the closer you need to be to a toilet
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The miracle supplement to fight sarcopenia is called, “pick up heavy things repeatedly.”
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And what is HMB’s mechanism of action? It’s a metabolite of leucine and is…drum roll…an mTOR activator!!!
I’ve toyed with it on/off over the years. The research is decidedly mixed for muscle building and seems more helpful in the elderly and less helpful (or not at all) in younger and/or experienced resistance trainees. It’s also expensive and probably doesn’t work any better than whey protein (which contains a whopping dose of actual leucine). I try to keep an eye on newer studies as they come out in case I see a reason to change my mind.
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I think that you are right in that this would be a supplement that works best for the elderly. Sarcopenia and Cognitive Decline are two very real and serious problems.
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Steve I’m 71,female and past 4 years have been dealing with broken femur and knee replacement that didn’t go well, but worse I have so much fatigue, so I’d surely be a candidate for this. Did you look into various brands? I’m not seeing it with the brands I trust. If it tastes awful I guess you could get it in capsule form?
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I’m not much of a brand kind of guy, for the most part. I get mine from;
As indicated by others, some studies indicate HMB may work best when the person is resistance training, additionally in combination with creatine. Not sure it would be of benefit if one was not exercising but who knows. I’d guess that if one did not see a difference in 60 days of use, it may not work under that persons lifestyle/regimen/condition. It would cost about $40 to find out.
There is a fair bit of research into sarcopenia (and dementia) with respect to beneficial dietary interventions.
I added inulin to my super duper breakfast shake about 2 years ago due to it’s potential gut biome support. It also contains beta-glucan and gum Arabic for the same and other reasons.
Dietary fiber intakes are generally too low in the general population and especially in older people, which may contribute to the main metabolic syndromes that accompany aging, such as sarcopenia. Note that caution is warranted when attempting to translate these findings from rats to humans, as there may be species-specific differences. … While more research is needed to fully understand the additional or even synergistic effects of plant-derived compounds such as proteins and fibers on muscle health during aging, there is already enough evidence to recommend combining intake of a high-quality protein with a sufficient fiber intake to protect muscle mass and function, and thus extend the autonomy of older people.
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Thanks Steve I do take creatine and in spite of fatigue am trying to get a bit of resistance training in. Just bought one of those old Health Riders for 25 bucks, you may not be old enough to remember them but they were big in the 80’s or 90’s. It really works the arms if holding on to post vs handle. I use blood restriction on my leg that had broken femur and disastrous knee replacement, but nothing seems to be bringing that leg back. Maybe that’s what Peter Attia means when he says falls over 65 some never are the same, and yet I have a friend not even as strong as I due to RA who broke her femur and totally back to pre fall 3 months later. Mine was 4 years ago. I wish Peter would say why this is when he gives statistics.
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I deleted this way because I forgot how too delete a post. I have never deleted a post that I can recall.
Have you been tested osteoporosis? I’m not a clinician by any stretch of the imagination but bone healing should not take that long unless something fundamental is out of wack… (scientific term)
Joints can take longer, ligaments and tendons have very low blood flow and low cell turnover and often require therapies that stimulate local blood flow.
This is one of the things that certain peptides are good for, tendons and ligaments. Check out BPC157 and TB500.
For basic fitness, body weight exercises would be helpful, squats without weights, light dumbells for curls and presses, even bands would probably be better than a Health Rider
It’s about loading the bones with weight. Just moving is not enough. Bones respond to the stress of weight bearing exercise.
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Yes I was tested after my femur break - it had been 7 years since a DEXA and was pleased no change but do have -2.5 in spine and 1.9 in other 2 places. -2.5 is last digit before osteoporosis. So not great, but not horrible. The only thing that could have held that for 7 years is estrogen or strontium.
Re the Health Rider, I was wondering about it’s not a weight, but it’s like using exercise bands where that arm is really tiring bringing that bar up. Which makes me wonder are exercise bands then not that good for preventing osteoporosis? I’d think anything that made one stronger? Course swimming makes one stronger yet I know it does nothing for osteoporosis. hummmm, never thought of this but maybe exercise bands aren’t the best for preventing bone loss.
My knee it just hasn’t worked, it aches, sharp pains, I knew something was wrong week 2. I’d had 6 previous ones decades ago so I knew how it was supposed to progress. The leg issue is muscle or maybe nerve, but MRI showed nothing. Bones have healed. I’ve been wondering what other modalities are out there that might help. The doc just thought it was due to weak muscles but I can lift 20 pounds of ankle weights, it’s not a weakness issue. I’ll try the the things you mentioned. Thank you!
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