This seems like a product that people could try themselves, doing comprehensive memory testing pre and post dosing, to test and gauge effectiveness. The side effects seem pretty benign, and smaller doses could be tried before working up to higher doses.
The FDA approved maraviroc in 2007 as an antiretroviral drug (ARV) for people with HIV infection.
HOW IS MARAVIROC TAKEN?
Maraviroc is taken by mouth as a tablet or oral solution. The recommended dosage of maraviroc for adults depends upon what other medications are taken. The dosages are:
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- 300 mg daily, taken as 150 mg twice daily
- 600 mg daily, taken as 300 mg twice daily
- 1,200 mg daily, taken as 600 mg twice daily
The standard dose is 600 mg daily taken as 300 mg twice daily, in combination with other ARVs. Your healthcare provider will decide which dosage regimen is best for you based on your medical conditions and the other medicines you take.
WHAT ARE THE SIDE EFFECTS?
When you start any ARV, you may have temporary side effects such as headaches, nausea, indigestion, or a general sense of feeling ill. These side effects usually get better or disappear over time.
The most common side effects of maraviroc in adults are colds and cold-like symptoms, cough, fever, rash, bloating and gas, indigestion, constipation, and dizziness.
Maraviroc can cause serious side effects including:
Serious liver problems (liver toxicity). Some people who take maraviroc can develop a severe rash or an allergic reaction before liver problems happen and may be life-threatening. Stop taking maraviroc and call your healthcare provider right away if you get any of the following signs or symptoms of liver problems:
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- An itchy rash on your body (allergic reaction)
- Your skin or the white part of your eyes turns yellow (jaundice)
- Dark or “tea-colored” urine
- Pale colored stools (bowel movements)
- Nausea or vomiting
- Pain, aching, or tenderness on the right side of your stomach area
Your healthcare provider will do blood tests to check your liver before you begin treatment with maraviroc and as needed during treatment with maraviroc.
Severe skin rash and allergic reactions. Severe and potentially life-threatening skin reactions and allergic reactions have been reported in some people taking maraviroc. If you develop a rash with any of the following symptoms, stop using maraviroc and contact your healthcare provider right away:
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- Fever
- Generally ill feeling
- Muscle aches
- Blisters or sores in your mouth
- Blisters or peeling of the skin
- Redness or swelling of the eyes
- Swelling of the mouth, face, or lips
- Problems breathing
- Yellowing of the skin or whites of your eyes
- Dark or tea-colored urine
- Pain, aching, or tenderness on the right side below the ribs
- Loss of appetite
- Nausea/vomiting
Heart problems, including heart attack.
Low blood pressure when standing up (postural hypotension). Low blood pressure can cause dizziness or fainting. You should avoid driving or operating heavy machinery if you have dizziness during treatment with maraviroc.
Source: maraviroc (Selzentry) – International Association of Providers of AIDS Care