Healthspan discussion on recent human trials of rapamycin

A discussion of human trials of rapamycin and a walk-through of 2025 studies specifically.

  • The PEARL trial: the first major human data on weekly low-dose rapamycin
  • Early cardiovascular benefits at low doses
  • Emerging research on long COVID and chronic fatigue
  • The mTOR pathway, explained simply
  • What animal studies (ITP) show vs. what we’re now seeing in humans
  • Dosing and bioavailability: why more isn’t always better
  • A year of safety data, explained
  • Trials to watch in 2026 and 2027
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