Hazel Szeto, SS-31 peptide, the World's First FDA-Approved Mitochondria-targeted Drug (Longevity Summit, 2025)

Yes paypal can send the popular coins but has a bias toward their own coin pyusd. Cash app just deals with bitcoin, BTC. Paypal i hear is the worst for banning users from sending crypto to drug vendors. Cash app just blocks you saying dangerous account.

That URL above for crypto training is good but these apps are not easy to use so the click by click steps are missing.

I chose Exodus as my soft wallet to hold crypto funds in wait prior to buying stuff. Few mention the 5 days ++ needed to get through KYC, know your customer, setup before you can buy coins. Or the lag time for funds to be “good funds”. So I move a sizable amount of cash through these apps and leave it. Yes a risk for being ripped off.

Much back and forth using cash app / paypal to send crypto TO Exodus I’ve decided that the easiest and lowest fees (treamendous losses to fees with multi hops) is to fund Exodus from WITHIN Exodus using their xfer app Moonpay. I’ve not had luck hooking a CC or debit card up to Moonpay but using Venmo under neath Moonpay.

EVERY tool needs KYC and 5 days to setup. The above within Exodus can take 10 days +/- 5 for KYC (can be shorter) for Exodus initially and another possible 5 for Moonpay. The quick verification of KYC never worked fast for me and always took many days. Maybe your electronic selfie can be electronically matched to your uploaded drivers license better then my DL and bad picture.

Glad to help over PM or email etc if you want to get these tools setup. Like Beth this qualifies as brain excersize doiing thinking things of “consequence” vs just sodocu puzzels.

Edging in a rant; this whole pitch about crypto being the future is such BS and crap! Slow, huge fees, insanely slow and not just BTC, monstrously complicated, too many tools. I can’t stop bitching about the huge falling short crypto has been!!! Avoid bitcoin, BTC, if you can. Vendors take many coins over many networks. USDC over Solana is often taken. Or Solana over of course solana. I used to think I was smart by storing long term in Exodus in Tether Gold, then gold dropped. I now give up and just store reserves in Solana. You need a small amount of solana if you send varioius coin types over solana to pay the fees anyway.

Good luckl, curt

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Hahahaa @curt504 I’ve been doing it and yet I only understood half of what you said… more brain exercising to do!

Instead of paying with Solana for my last order from PGB, and losing a little bit of value during the process due to currency fluctuations, I tried to keep it all in stablecoin… I couldn’t figure out how to pay and just gave up.

I don’t actually need anything but am thinking of stocking up incase it eventually gets harder to get things in the country.

I’m really here to comment that I’ve experienced the things you’ve mentioned.

I’ve purchased crypto through venmo, PayPal, and coinbase… each and every one of those places has frozen my transfers and cost me money during the time while my crypto was stuck in purgatory (and why I tried to keep it all in stablecoin last time). I ultimately send the crypto to exodus before paying. So yes, they freeze my transfers even sending my own money to my own wallet… grrrrrr.

I mostly try to use coinbase becasue I’m told the fees are lower, but I haven’t done it enough times to really know

The least expensive way, so I’m told, is to somehow buy solana within the exodus app… you go to an entirely different section… I looked but it was WAY too confusing for my old ADD brain :slight_smile: One day I hope to learn just for the sake of learning. Maybe Claude can teach me!

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After posting the above I looked at my fees for funding $1000 into solana in Exodus; 3 layers, total fees where $96. Only $994 arrived. I went nutz and chatted in the Luther (peptide vendor on whatsapp, better then PGB, wider if not every peptide) crypto sub group. After googling I’m doiing this:

Moving to Kracken Pro, which unlike Exodus, supports native (integral to the app) ACH from a bank account. Free xfer with a few day ACH lag.

Sad, that funding Exodus via the many means: cash app sending BTC, paypal sending PYUSD, worse choice is the integral Moonpay under Exodus. Exodus is an ok wallet and xfer fees are tolerable its just so expensive to get funds unto an Exodus wallet from what ever tool you use.

Best of luck, curt

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There are lots of problems with crypto, but the transactional costs are much higher than the banking system.

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Bitcoin is terrible for buying drugs: network is too slow, fees are too high, and it’s too volatile.

Cheapest network is still Solana. Cheapest way to buy crypto is still to buy PYUSD on paypal, send to your Solana address, and optionally swap for your vendor’s preferred stablecoin. Takes me 2-3 minutes to do the above when I’m ready to buy. The transaction cost is usually less than 0.1 cents.

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Just reporting: setup Kracken Pro, funded from bank acct ACH $500. $500 arrived instantly. Bought $500 of solana, got $498 worth of Solana. Dug for the fee: $1.78. Still is 3.4% fee, but beats my prior worst fee paid of $96 on $1000, 9.6% fee all said in Exodus via moonpay via venmo via direct from bank acct.

All these apps used the same design guide; max confusion, hide or not implement obvious things. Make actions hard to figure out. Force you to google every small todo. ;( ;( ;(

In Kracken Pro looks like to send crypto to a rremote address (some vendor) its called a Withdraw. Paste the address or scan the QR code.

Good luck, curt

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Good tip. I gave up on cash app / paypal assuming funding fees are too high. This may be a good scenario for other crypto newbies. My torturous path I can’t recomend.

tnx for posting. I’ll experiment to see my transaction costs with this path, Curt

Can you spoon-feed me a bit here.

Buy PYUSD in PayPal, got it.

Send to my solana address (I don’t think you mean exodus, so where is this being sent to exactly?)

And after it is there, then I swap PYUSD to, for example, USDC… right?

And then I send it to the vendor.

If you have an Exodus wallet, you also have a Solana address (and a ETH address, and a Tron address, etc). To find your Solana address, go to any holdings you have in Solana network on Exodus, and press the receive button. That should show your address that sou should be able to copy.

AH, eureka…

So, I buy PYSUD

I send PYSUD to my solana address within Exodus

Then once in there, I swap it to USDC… and send it out from there…

I guess I assumed if in solana, I had to, um, buy solana :).

This is great, thank you!

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The list price for the branded version of SS-31:

HFeoGo8WcAA0448

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By frozen do you mean delayed or something else? I’ve never had a problem with Coinbase. I just keep enough cash in USDC to make an occasional purchase after which I re-supply more cash to USDC. Unless required I don’t specifically convert my USDC to Bitcoin for a purchase. It’s a fairly simple process to me, but if you’ve found a better system tell me about it.

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I’ve had multiple things happen.

I had a reasonable limit on my debit carb that I linked to fund coinbase and it worked really well a couple of times… but then

And I can’t remember the order of events…

one time it just delayed moving my assets over to my wallet… maybe it was a week (calling that frozen).

Then another time it showed ApplePay was an option to fund my coinbase, so I tried that… it failed becasue you can’t use Apple Pay :), and then it effected my other limits! I can now only move $50 at a time from my linked debit card and then it will will say $0 limit for several days… and then eventually it will say $50 again…

I have since linked PayPal and that limit is $1k, but PayPal charges a fee to move money over, so that seems pointless.

GAH!

I should contact them but I assume they will be as helpful as PayPal when they have held my xfers for a week … which means not helpful

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The Branded version of $$-31…FDA* approved.

*FDA: Failure, Deception, Abuse

Given Colwyn’s response, I guess you don’t want to wait until you’re too old to start fixing your mitochondria with SS-31…

I asked Colwyn, what is your take on the potential for SS-31 to help in aging-related mitochondrial dysfunction?

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Perhaps a good example of why people shouldn’t go to TikTok for medical advice?

People Online Are Injecting This Popular Peptide to Improve Their Vision

Some are claiming the peptide has also helped their astigmatism.

Key Points

  • TikTokers are using a peptide called SS-31 for their eye health.
  • SS-31 technically has FDA approval. However, it is used for a rare mitochondrial disease. Recent research looking at SS-31 to protect the retina found the drug was ineffective.
  • As more people stay indoors and look at screens, the number of myopia (nearsightedness) cases is expected to rise.

IF YOU ARE squinting to see TikTok, you may be wondering about the peptide elamipretide (SS-31). Right now, the platform is buzzing over this peptide elamipretide and its purported effects on improving eyesight. Some people on the app have even claimed that the peptide improved their astigmatism, a common eye condition that leads to blurry vision.

“I want to see if my eyes are improving in some way on SS-31,” said one poster. “Light sensitivity—computer screen light, blue light—it seems to be less bothersome, where my eyes can actually focus on light a little bit better.”

YET DOCTORS AREN’T convinced that SS-31 lives up to the vision-changing claims. That being said, they are keeping an eye on SS-31 for a different type of eye health issue. “Elamipretide is being investigated for improvement of age-related macular degeneration (AMD), not ‘aging eyes,’” says Jeffrey J. Walline, OD, PhD, an optometrist and the associate dean for research at The Ohio State University College of Optometry.

For AMD, Dr. Walline says the drug is experimentally injected into the eye to protect the retina. This is the part inside the eye that helps you see. “An initial phase 2 investigation reported that the drug did not meet any of its endpoints, indicating the drug was ineffective,” he points out. “The follow-up study has not been completed, so no results regarding elamipretide’s effectiveness for improving vision loss secondary to AMD are available.”

While the trial is still ongoing, there are a few takeaways worth noting. One: A whopping 86 percent of people in this clinical trial had side effects. Two, people taking SS-31 to improve their eyesight weren’t injecting the peptide into their eyes.

Dr. Walline stresses that while AMD can impact your vision, it’s not the same as needing vision correction. “Elamipretide does not have anything to do with astigmatism or presbyopia, a condition when people over 40 years old have difficulty reading close print.”

Raj Maturi, MD, clinical spokesperson for the American Academy of Ophthalmology and ophthalmologist at Midwest Eye Institute, stresses that SS-31 is not an “established treatment” for common vision issues like myopia (nearsightedness), presbyopia, or astigmatism.“Those problems are optical and structural,” explains Dr. Maturi. “A mitochondrial peptide is not expected to reverse those underlying vision conditions.”

SS-31 may help slow down macular degeneration in theory, says Bavand Youssefzadeh, DO, an ophthalmologist at Global Lasik and Cateract Institute in Huntington Beach, CA. But again, the research hasn’t proven it and this is very different from issues like nearsightedness and astigmatism. “This is not a general eyesight improver,” Youssefzadeh says.

Read the full story: People Online Are Injecting This Popular Peptide to Improve Their Vision (Men’s Health)

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You’ll be the first to hear if my astigmatism goes away

Reason #1M I’m happy not to have a TikTok account.

Peter Attia’s recent take on SS-31, from his AMA:

Peptide case study—SS-31: mechanism of action, approved use in Barth syndrome, and other claimed effects [18:15]

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Is anyone here realizing benefit from this peptide? Attia says the data show benefits only for those who have Barth syndrome.

GHK-cu is a tripeptide.