Butterfly IQ has cheap machines, tho probably not useful for this
also prophetic.ai
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a potential breakthrough being tested on humans, not mice.
Revolutionizing Alzheimerās Treatment: Breakthroughs with Focused Ultrasound (2024)
Suzanne LeBlang, MD, a leading neuroradiologist and Director of Clinical Relationships at the Focused Ultrasound Foundation, delivers an an in-depth overview of how focused ultrasound technology is opening new doors for Alzheimerās treatment.
Discover how this innovative approach is used to safely open the blood-brain barrier, allowing for effective drug delivery and potential reduction in amyloid plaques. With insights into the results from various global studies and the promising future of focused ultrasound in neurodegenerative disease treatment, this presentation is a must-watch for healthcare professionals, researchers, patients, and anyone interested in the latest in Alzheimerās care.
Website:
just published bombshell papers on tFUS and waste clearance Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models | Nature Biotechnology
This post was ahead of its time!!
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Iāve often told people about the great mass of literature showing that low intensity ultrasound has all kinds of anti-inflammatory benefits in the brain; irrespective of neuromodulation. In the this weeks episode of FUS Forward, Charles Caskey and I catch up with Raag Airan on his new findings where he treats the brain with ultrasound following hemorrhagic stroke. From particles to fluid flow, ion channels to sociopaths, I promise this episode will change the way you think about ultrasound brain stimulation. Links below
Transcranial Low-Intensity Focused Ultrasound (LIFU) is a precise, non-invasive tool for neurodegenerative clearance. Research shows that 500 kHz pulses significantly accelerate meningeal lymphatic drainage in Alzheimerās models.
The mechanism uses microbubble cavitation to drive cerebrospinal fluid into the brain parenchyma. This stimulus upregulates lymphatic endothelial markers LYVE-1 and Prox-1 by 3-fold, optimizing waste-removal pathways.
LIFU also restores aquaporin-4 (AQP4) polarization on astrocytic endfeet. This facilitates the export of proteopathic aggregates toward the deep cervical lymph nodes.
Data reveals a 35% reduction in amyloid-Ī² plaques after four weeks. Crucially, MRI analysis confirms this clearance occurs without blood-brain barrier disruption or neuronal damage.
Subjects showed a 28% improvement in cognitive latency. Mechanical stimulation of the meningeal lymphatics offers a scalable, drug-free frontier for treating neurodegeneration.