Interesting tweet from Gordan Lauc from Glycanage
https://twitter.com/GordanLauc/status/1731195348406751719
https://www.nature.com/articles/s41586-023-06749-3
@rapadmin why don’t these links get embedded?
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Table from the article.
| Name | Physiological concentration | Working |
|---|---|---|
| concentration | ||
| Alpha-linolenic acid (ALA) | 18.5 +/- 7.9 uM | 37uM |
| Arachidonic acid | 55.4 +/- 4.48 uM | 110.8uM |
| Astaxanthin | 0.092 +/- 0.025 uM | 0.184uM |
| cis-Vaccenic acid | 10.7 +/- 5 uM | 21.4uM |
| Coconut oil | － | 800mg/L |
| Docosahexaenoic Acid (DHA) | 94.2 +/- 31.3 uM | 188.4uM |
| Docosapentaenoic acid (DPA) | 9.0 (7.3-11.5) uM | 18uM |
| Eicosatrienoic Acid | 3.61 +/- 2.1 uM | 7.22uM |
| Eicosapentaenoic Acid (EPA) | 11.0 +/- 8.3 uM | 22uM |
| Erucic acid | 1.264 +/- 1.590 uM | 2.58uM |
| Evening primrose oil | － | 200mg/L |
| Flax seed oil | － | 260mg/L |
| Gamma linolenic acid (GLA) | 1.08 +/- 1.5 uM | 2.16uM |
| linoleic acid (CLA) | 264 +/- 17.0 uM | 528uM |
| Myristic Acid | 25.0 (8.0-70.0) uM | 50uM |
| Myristoleic acid | 2.016 +/- 0.733 uM | 4.032uM |
| Nervonic acid | 0.900 +/- 0.974 uM | 1.8uM |
| Oleic acid | 122 +/- 56 uM | 244uM |
| Palmitic Acid | 122 +/- 48 uM | 244uM |
| Palmitoleic acid | 31.0 (5.0-85.0) uM | 62uM |
| Pumpkin seed oil | － | 400mg/L |
| Stearic Acid | 85 (31-470) uM | 170uM |
| Stearidonic acid | 0.408 +/- 0.4 uM | 0.816uM |
| trans-Vaccenic acid | 10.7 +/- 5 uM | 21.4uM |
| alpha-lipoic acid | 0.077 +/- 0.017 uM | 0.154uM |
| CoQ-10 | 4.31 +/- 0.42 uM | 8.62uM |
| Inositol | N/A | 120mg/L |
| L-glutathione | 800.50 +/- 201.73 uM | 1601uM |
| Lutein | 0.52 (0.24-0.79) uM | 1.04uM |
| Lycopene | 0.743 +/- 0.168 uM | 1.486uM |
| L-α-Phosphatidylcholine | N/A | 84mg/L |
| Pterostibene | N/A | 10mg/L |
| Quercetin | 0.06 +/- 0.03 uM | 0.12uM |
| Thymoquinone | N/A | 200mg/L |
| Trimethylglycine | N/A | 130mg/L |
| Ubiquinol | N/A | 20mg/L |
| Zeaxanthin | 0.04 +/- 0.04 uM | 0.08uM |
| 6-gingerol | N/A | 5.5mg/L |
| Boswellia Serrata Extract | - | 90mg/L |
| Bromelain from pineapple stem | - | 100mg/L |
| Caffeic acid phenethyl ester | - | 0.012mg/L |
| capsaicin | N/A | 100mg/L |
Lowest working concentration seems to be astaxanthin, zeaxanthin, and quercetin.
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I’m not sure that red meat is a big factor in cancer prevention. But, as a lifelong red meat eater who has never had cancer except for a minor skin cancer from sun exposure, it hasn’t done me any harm so far.
I do believe red meat has something to do with my lack of any noticeable sarcopenia.
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Hmmmm… pound of steak every other day… big glasses of milk every day.
My DEXA - normal BMI - strong bones, Coronary Calcium Scan - zero, and Blood panels Levine score under 50 years, GlycanAge 42 years, TruMe 51 years… at 65.5 chronological years …indicates this diet is working great past decade plus for me.
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