If purchased from Japan, Voquezna (Takecab/vonoprazan) would cost about $40 per month at 20 mg per day with a 500 pill purchase. The study below found it was effective at 10 mg. If so, as little as $20 per month if 20 mg pills are cut in half.
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From a published literature review, October 2022:
“This article concludes that VPZ (Voquezna) is superior to PPI in terms of efficacy, safety and cost-effectiveness in reflux disorders and H. pylori eradication. Hence, use of vonoprazan should be preferred over conventional PPIs in these disorders.”
Vonoprazen was familiar to me and now I remember why:
Efficacy of Vonoprazan for Helicobacter pylori Eradication - PMC.
Asian countries seem to be way ahead of the us and europe when it comes to treating upper GI issues. Stomach cancer is much more common in asia. H pylori is the most common cause of gerd, lpr, and stomach adenocarcinoma. The recommended therapy keeps changing and usually includes at least two antibiotics plus a ppi plus bismuth.