Rapamycin to Reduce Grey Hair
In my May 22, 2023 update in this post, I discussed a US study that found that topically applied rapamycin (sirolimus) could reverse grey hair via mTORC1 inhibition. I also covered rapamycin in my post on autophagy. In recent years, the compound has been heavily researched for its anti-aging properties.
Now we have yet another study with similar findings. At the 14th World Congress for Hair Research at the end of last month, Dr. Andy Goren made a presentation titled “Repigmentation of Grey Hair.” In it, he discussed a small 10-person proof of concept study for oral rapamycin as a potential treatment for early hair graying. The dosage was 0.5 mg every other day, and the male and female volunteers all had less than 30% grey hair. Of the 10 participants, 6 saw an improvement in grey hair within 30 days.
Check out the 4 slides here for more details. Dr. Goren’s Instagram also has a related slide titled: “Fifty Shades of Grey. The Sirolimus Effect: Targeting mTOR Pathway in Premature Hair Greying.”
Read the full blog post here: Can you Reverse Grey Hair? New Updates. | Hair Loss Cure 2020




