FDA-Approved Drug Combo Rescues Alzheimer’s in Mice

#1

scientists from the University of California San Francisco set out to find existing drugs that would be effective against Alzheimer’s disease.
The immunosuppressant rapamycin (sirolimus), known for its anti-aging properties, also made the cut

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#2

Thanks. The paper: Cell-type-directed network-correcting combination therapy for Alzheimer’s disease 2025

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#3

Interesting given that the forum has been very pro-estrogen and letrozole is a powerful aromatase inhibitor.

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#4

It’s interesting to see that one of the other identified compounds is an antifungal agent (ciclopirox) but we know that rapamycin is also an antifungal agent and that fungi (Candida, etc.) is found in Alzheimer’s brains.

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