Faulty mitochondria cause deadly diseases: fixing them is about to get a lot easier (Nature)

Full open access article here:

https://www.nature.com/articles/d41586-025-03307-x

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Tnx! Just name dropping. All of these/this has big youtube foot print for dose and protocol. The Body builders have long moved past steriods into even mitochondria boosts.

  • Injected peptides: 1mg to 10mg MOTSC. Dosing from 1x / wk at 10mg, to 1mg / day 5x week.

  • Injected: SS-31, 1-2mg / day. But not on same days as MOTSC. Can do 1 week of ss-31, 1 week of MOTSC.

  • Oral; BAM-15 + SLU-PP-332. Some combine on same days as above. Some suggest cycling so take these on Sat/Sun when not the above.

  • Methlene Blue. Wide dose range. Some say 15mg/day, continuous is good. Some say 7mg continuous but the Alzhimers prevention studies where at 15mg/day. Many experts give protocols and specific reasons for 30mg even higher but I would take their study and reasons into acount at 30+mg. It can be an antibiotic at some number 30+mg/day. This might be 50mg+. I stay 7-15mg/day.

  • Urolithin-a. An odd one. The Time folks say every day. Some health experts cycle opposite BAM-15/SLU.

  • Just read; high phenolic olive oil on a tablespoon / 3 hrs has a mitophogy effect and amplifies 12 hr fasting benefits. Something to add on your scenolitic period.

IMHO there needs to be more science in this mito-soup of nutricals area. Least of all how bad are your Mitos and what do they need??? I only know of a Mito function test by Chris Masterjohn Phd, $500 ish. My wife is considering. Weight loss, neuro function has a large mitochondria function.

Best, curt

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