Ezetimibe Reduces Long-term Cancer risk

Here’s another good reason to add ezetimibe to your ‘stack’ :blush:

Table 3 in the paper shown below, ‘teases’ out the effect of ezetimibe (from those who use statin+ezetimibe) on cancer risk

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From the charts it appears that ezetimibe is the major factor not the statin.

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Ezetimibe is a no-brainer adjunct to any lipid-lowering protocol!

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I don’t want to rain on the ezetemibe parade, but I did notice a couple of things in the study that I feel are worth putting out.

First this quote from the study: "Importantly, while the initial comparison between statin/ ezetimibe users and statin/ezetimibe nonusers demonstrated a statistically significant benefit at both 5 and 10 years, **this design does not allow for direct isolation of the effect of ezet-imibe, as the comparison group included both statin users and nonusers.

And then there’s the fact that after 10 years the curves are almost the at the same level.

I won’t stop taking ezetemibe, but I wish the evidence for it’s anticancer effects was even stronger.

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Yes, I concider that a weakness in the study. Absent that, the statin alone didn’t do anything statistically significant. I must assume until proven otherwise that it was the ezetimibe producing the results.

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