Experimental and real-world evidence supporting the computational repurposing of bumetanide for *APOE4*-related Alzheimer’s disease

Starting this as a new thread as it gets buried

*Published: 11 October 2021

https://www.nature.com/articles/s43587-021-00122-7

And the Correction

https://www.nature.com/articles/s43587-021-00144-1

“If you wait until you are ready, it is almost certainly too late.”
~ Seth Godin

I think it’s important to read this as well.

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Hi Joseph. I’m a 4/4 so I’m interested to learn what this means. Those articles are behind a paywall and I’m not schooled in reading scientific papers. I wonder if you could give a brief outline of what it’s all about?

The problem is the risk-reward ratio is not as good as some of the drugs we discuss here.
It’s very problematic unless you feel you are at a high risk of getting Alzheimer’s.

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