Looks like eating eggs, which are naturally high in cholesterol should not be a problem even if you are a high dietary cholesterol absorber… as long as you take ezetimibe! At least that’s the thought that occurs to me when I read about the potential negative liver health impact of dietary cholesterol (see the article below). Ezetimibe is not mentioned in the article, but seems reasonable to take into account. I think this is good news for egg lovers on ezetimibe who might be worried about consuming eggs. Of course there might be other issues, such as animal protein and high methionine levels. But another ezetimibe win in my book - preventing dietary cholesterol from reaching the portal vein, and stopping the absorption in the small intestine - as relates to liver health.
How Eating Eggs Affects Your Liver Health: Insights from a Hepatologist
https://www.aol.com/articles/eating-eggs-affects-liver-health-202500000
"The cholesterol in eggs is where it gets tricky. Dr. Brown points out that eggs are high in cholesterol, and high cholesterol forces the liver to work harder and can cause fat buildup.
“Because of this, the answer to whether or not eggs are good for liver health really depends on someone’s overall diet and their metabolic health,” he says, explaining that if someone is in good health and eats a wide variety of nutrient-rich foods, eggs can have a healthy place in their diet. But if someone has high cholesterol, they may want to eat eggs less frequently."
"One study published in the World Journal of Hepatology included 169 people with MASLD and 782 adults who did not have it. All of the participants were asked how often they ate eggs. Researchers found that people who ate two to three eggs a week were more than three times more likely to have MASLD than those who ate less than two eggs a week.
But Dr. Brown highlights a bigger, more robust study taking into account 1,414 people, which found no association between egg intake and MASLD. In fact, the researchers found that the choline in eggs helped protect against MASLD.
Why the conflicting data? Dr. Brown reiterates that what one’s entire diet looks like matters; protecting your liver doesn’t come down to one singular food. He also emphasizes that what one’s individual health looks like matters greatly too.
If you have low cholesterol and are in good health, eating an egg or two every day likely isn’t going to be detrimental. But if you have high cholesterol, it’s likely best to eat them more moderately and not every day."