Edit Human DNA at Home With a DIY CRISPR Kit


Wow - very interesting. Not something I’d recommend for most people, but definitely interesting. Seems like there is going to be a market opportunity for another business selling the longevity gene segments that people then add to a viral, or non-viral, vector for delivery…

Though to be honest, I suspect most people, as this technology progresses, would prefer to go to a clinic like Minicircle for these types of procedures… Our Therapies - Minicircle

Currently, eight genes (BUB1B, CISD2, KLOTHO, PAWR, PPARG, PTEN, SIRT1, and SIRT6) are listed as pro-longevity genes by the Human Aging Genomic Resources, which means that they have been experimentally demonstrated to mediate lifespan in mammals.


So which gene do we edit to regrow hair?

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This is a bit worrying from a pandemic risk perspective.
If “DYI” CRISPR is widely available at home, and for such a small amount.

You mean from a person creating or modifying their own viruses?

I suspect you’d have to be a very good virologist to understand how to do the “gain of function” type of research that is done in bioweapons labs, so not a concern for the average biohacker. But longer term an issue for rogue actors with good connections with biologists.

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Yeah, growing and modifying viruses, or something else. Genomic sequencing is decreasing cost wise exponentially. So rogue actors will apparently be able to modify viruses with this and eventually sequence the changes. Maybe this is science fiction territory, but maybe the competence barrier is a mirage with a better but ‘black market’ ChatGPT in 5-10 years.

Prepping might become a longevity strategy. :confused:

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You are aware “CRISPR” is/was from the yogurt industry.


Anyone can purchase a portable, real-time device for DNA and RNA sequencing that connects to a lap top for around $1,000.00 with software.

More news on Longevity Genes:

Open Longevity Foundation Announces Open Genes Database

This is a comprehensive database of genes associated with aging and longevity.

Open Longevity Foundation released a novel database of genes involved in human aging and longevity — Open Genes. It includes information of more than 2,400 genes, which is the most extensive mapping of human genetics of aging to date. Open Genes provides comprehensive analysis of all human genes involved in major aging processes, contribution into life expectancy and genetic interventions, which affect lifespan of model animals. Open Genes is designed for a wide range of people interested in aging biology, and provides a potent tool for scientists working on the problems of aging and life extension.

The Open Genes database is created to provide the most comprehensive information on genes involved in aging processes, as well as to enhance and simplify the search for potential aging therapy targets. The database includes a detailed description for genes: lifespan-extending interventions, aging-related changes, longevity associations, connections to diseases and hallmarks of aging, gene evolution and functions of gene products. It aims to combine all available data on the genetics of aging and provide convenient tools for searching, assorting, and comparing genes. It describes 2,402 age-related genes, from 1,700 unique research articles; more than 2,000 genetic interventions, affecting lifespan of model animals, 4,648 records of age-related changes in gene activity, 1,458 records on longevity associations with gene variants. Data on each gene associated with aging is much more diverse and detailed than in existing databases (GeneAge, Digital Ageing Atlas, LongevityMap).