Sure it’s a crutch (ie it can’t be any better for your health than a real 5-day water only fast), but it’s still a useful crutch for many who wouldn’t do a fast otherwise.
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A few years ago, I did the 5 day fast for 3 consecutive months, which he recommends in his book. I didn’t use his food, just had a protein bar each day.
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I am a fan also. I still have three packages left.
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Dr. GREEN (rapamycintherapy.com) would agree and told me with my prostate cancer (non aggressive) that R will likely slow the spread but neither cure nor stop it. Because it’s use reduces senescent cell conversion by ~30%, it likely is something of a preventative to delay the onset and premature development of cancer.
Having been a smoker, any thing to delay is a win.
Review Dr. SARAH Hallberg’s interview with Dr. PETER Attie on You Tube about how to manage a cancer diagnosis… so not be as she said, ‘a sitting duck’ one you’ve completed your initial cancer treatment!
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Here is my N=1 data. Was diagnosed with Prostate cancer 3/2014
Rather than get surgery, I researched and settled on metformin and diet. About 4 years ago I added rapamycin.
MRI’s and testing had shown no progression and a Galleri test last month couldn’t detect any cancer.
Even my PSA is at its lowest levels in 11 years.
I take 10 mg every 10 days. Stopped metformin about a year ago and switched to Jardiance 25 mg
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@Paul question for you on managing the 10 day rapa dosing schedule. How do you do it? I’m having a devil of a time shifting my schedule every week. Workouts, meal schedules, etc. Any secrets? Perhaps you don’t worry about those details.
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I have a large spreadsheet - record about 20 biometrics every morning
so I record when I take rapamycin and its easy to see 10 day increment
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Periactin for cancer? N = 1.
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The Beatles were heavy smokers. George Harrison died of lung cancer. Paul & Ringo are doing great.
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Exactly. When he stopped taking rapamycin, the tumors came back quickly
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Do we know for sure that he stopped taking rapamycin?
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This is as per the statements of his son Ajai Sehgal. See comments # 43 and 53 in this thread above.
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Yes. He said it himself.
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Yes, that’s definitely what he said. The odds are extraordinarily high that they would’ve come back just the same had he never stop taking rapamycin.
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Love you reasoning. This is where I’m at too. Until absolutely necessary I’ll stick with my exercise-diet-supplement-rest routine and have as much fun as I can. Rapa would be difficult and costly for me to get at the moment, so it’s still pending.
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Brad Stanfield does a pretty good job of analysing this paper:
And one of the authors on the paper says:
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Peter Attia good agree with everything Brad say about the paper and still he comes to the opposite conclusion. Why take some thing with no proven benefits if there is even a tiny risk?
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Are there any updates on M Blagosklonny’s health status? Looks like he stopped posting on Twitter at the end of July.
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I would love to see a reference for the claim that mTOR is generally higher in mice than humans. I haven’t seen such a reference.
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It is a sample size of 1 and it tells us nothing.
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