Meanwhile Alan Green has endorsed Taurine supplementation on his website. I have high regard for both of these men even though their opinions differ. Dr. Attia is more cautious. Although he takes Rapamycin, he does not prescribe it for patients as far as I know. Dr. Green will jump on a new discovery very quickly if he evaluates it as low risk with possible reward. Dr. Green also endorsed the use of Glynac soon after Mayo published their study.
If Dr. Attia is right the Taurine supplement may be a waste of money excreted in the urine. For those of us with money to burn (or urinate away), Taurine is worth a shot.
Dr. Attia recommends Taurine for those who are deficient, such as vegetarians.
There are a lot of vegetarians here.
Taurine is cheap. For those of us buying rapamycin and other pharmaceuticals Taurine is a small fraction of the budget.
No, he does.
“A small but growing number of people, including me and a handful of my patients, already take rapamycin off-label for its potential geroprotective benefits. I can’t speak for everyone, but taking it cyclically does appear to reduce unwanted side effects, in my experience.”
Outlive: The Science and Art of Longevity
I continue with Taurine. I find Taurine performance enhancing + there are a huge bulk of science indicating that Taurine is beneficial for many orrgansystems in humans. Nobody know if it increases lifespan in humans. But the effect of Taurine on mitochondria alone, is a good enough reason for me to continue taking it. + there is a very limited downside.
“Mitochondrial dysfunction, along with oxidative stress, is a key hallmark of various pathologies, such as aging [1,2], cardiovascular diseases [3,4], mitochondrial diseases [5,6], metabolic syndrome [7,8], cancer [9,10] and neurological disorders, such as neurodegenerative diseases [11,12] and neurodevelopmental disorders [13,14]. Often, antioxidant therapy, such as coenzyme Q , mitoQ [16,17], vitamin E , gingko biloba extracts , ebselen , creatine , lipoic acid , melatonin [23,24] and l-arginine [25,26], provide some protections, potentially by improving the mitochondrial function and reducing oxidative stress in these diseases. Recently, taurine, a sulfur-containing amino acid, has been approved in Japan in treating stroke-like episodes in patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS), which is a mitochondrial disease [27,28]. Indeed, the use of taurine dates back to 1985, as taurine was first used to treat patients with congestive heart failure in Japan [29,30]. In addition, taurine supplementation has been shown to improve the exercise capacity of patients with heart failure , which is likely due to improvement of the myocardial energy production. Although taurine was first identified in the 1800s , the mitochondrial actions of taurine still remain unclear and underappreciated. This review, therefore, will provide an overview of the significant role of taurine in the maintenance of mitochondrial function. Clinical studies using taurine therapy in mitochondria-targeted pathologies will also be discussed.”
It’s an inexpensive amino acid. It may have great health benefits. It may not. As long as there are no significant side effects, I am happy to take it. My taurine powder arrived two days ago.
Unfortunately, I have noticed I have become more irritable in the last two days since I started taking it.
I will continue to use the batch I ordered and then re-evaluate it when I run out.
I take large dose 1,5 gr - 2,5 gr at night, before going to bed. (Taurine in large amounts has a cognitiv effect on me. It makes me sleepy). I also take small amounts before aerobic exerise.
Taurine affects the brain, through the GABA neurotransmitter receptors. it can influence mood, sleep anxiety etc.
I’m sceptical, but as I’m doing a lot of sports, I think about it trying it since 3 months or so.
the reason for my scepticism is just:
I have tested switching to a vegan diet. No effects on sportiness, but it felt like I’m starving due to the methionine and leucin restriction → so total portein intake increased a lot to counterbalance it).
I’ve tested eating a lot of whey protein with tones of methionine. No effects on sportiness.
I’ve tested a diet rich in flesh and animal products. No effects on sportniess (but … UGH!!! can’t see it anymore)
I’ve tested eating tons of diary products like curd and yoghurt: no effect at all.
I actually eat a lot of seafood and I will switch to a mostly vegan diet again.
Why should a supplement do any better then a diet rich in animal products compared to a mostly vegan diet? At least there is not any improvement in my sportniess. If there is an improvment, its probably not in ones sportniness - or at least not in mine.
My sports programm:
8-20h martial arts training per week (from medium to very high intensity incl sparring)
1-3h resistant training per week (mostly gymnastic rings but also resistant band and dumbbell excercises).
if I will try taurine, I’ll let you know.
I apologize for the diversion, but @Qurestine you do 20 hours of martial arts training per week? Plus 1-3 hours of weight training? — that is SERIOUSLY impressive (unless you are a professional or Olympic martial arts competitor, and then I’d ignorantly guess these levels are…ummm, average?). In the summer I often hike 10-25 hours per week plus 3 hours of weight training (more in winter plus stairs), but that is a much lower intensity of physical activity (and I’d argue my weight training can be at least 2/3rds resting for my next set). And I thought I was in pretty good shape…
I think this is the right question. I am addicted to supplements but am working hard to eliminate as many as I can by looking for the ones that are not supported by hard data or that I can get though food. When I need more than my diet will provide, I will supplement with reliable pharmaceuticals or nutraceuticals. This is my goal, anyway.
my average is ~12h per week martial arts training, but it strongly depends on the intensity of the training. And no, I’m not a professional, but I think I have a mild athlete’s heart.
Btw I like hiking to, esp on mountains. Unfortunatly I’m living in the lowlands.
@Joseph_Lavelle I could be addicted too, but theres a mild voice in my head saying all the time: “interactions, interactions you damned damsel!”
21 supps, 3 from in-house production. But I take only 6-8 per day.
I did martial arts for 30 years. Loved it. Loved sparring.
And here’s a study on taurine and the kidneys, a concern of mine. Looks like a good risk/reward ratio.
Which has more credibility Attia’s “opinion” or a peer reviewed published study?
If you wait until you are ready, it is almost certainly too late.”
~ Seth Godin
I am not the waiting type.
For what it’s worth I found the research on Taurine compelling enough to consider taking (mostly for sports performance) prior to this study existing.
IMO, taurine is extremely favorable on the risk reward spectrum. Yes, the reward may not be that high, but the risk appears low.
As with most supplements, I ask myself : how does this improvement compares to the one brought on by exercise? Bonus question : does more exercise lead to more endogenous production of said supplement?
Since I’ve started taking taurine a couple of weeks ago (1.5-2 grams) at night, I have had markedly more vivid dreams. Has anyone else experienced this?
I noticed it but I wasnt sure which supplement was the cause. And 2g made it worse than 1g
Sign me up.