Dr. Alan Green, a great pioneer in Rapamycin usage, passed away yesterday in Little Neck, NY

Dr. Green died yesterday. He was a brilliant doctor, a tireless advocate and a friend.

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So sorry to hear it. He made his mark. RIP.

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Yes sorry to hear that. His webpage finally convinced me to take Rapamycin. RIP

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I’m saddened to hear this news. Memory Eternal.

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Thank you for the update. Very sorry to hear this. He really moved the longevity field forward.

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I was patient #139. I live better today because of his kindness.

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He was a great man and a pioneer of Rapamycin. He will be missed. 80 yo. RIP

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Very sad news. He helped a lot of people (myself included) and really seemed to have found joy in his work.

He will always be remembered fondly by the rapamycin community as he served so many of its early (longevity minded) users.

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May he rest in peace .I wouldn’t have learnt about something as amazing as Rapa and wouldn’t have come to this amazing forum without him!

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He was a good man. If anyone has a link to his obituary and/or details on his funeral arrangements, can you please post here or message me?

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Yes very sad. Also should we be worried?

Two of rapamycin pioneers, Dr Alan Green and Dr. Mikhail V. Blagosklonny both are not exactly longevity models thus far. 80 is very young by today’s standard.

Do we know the details?

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Dr. Green has always been in poor health due to his heart condition. It’s amazing that he made it this long. There is nothing about his demise that will discourage me from taking Rapamycin.

Not everyone taking Rapamycin will make it to 100.

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Remind me what his heart situation was? I am just surprised as unless it is a heart attack, cardiology has come a long way and there are a lot of advanced interventions.

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I don’t remember that he specifically mentioned what the exact heart problem was only that it was an early stage of an extremely rare form of cardiomyopathy that runs in his family. He was in poor shape when he started taking rapamycin but managed an additional 8 years. 2016-2024.
He was retired and decided to restart his practice so that he could share with others and provide prescriptions for rapamycin to those who had some knowledge and wanted to try rapamycin
He first mentions his condition at about 5 min 39sec in this video.

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This is from his webpage https://rapamycintherapy.com/

“January 2016 at age 72, I started treatment on a regime of 6 mg of Sirolimus, once a week for apical hypertrophic cardiomyopathy. This is a very rare autosomal dominant heart disease for which there is no known medical treatment.”

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Gork:
Apical Hypertrophic Cardiomyopathy (AHCM):

Treatment:

  • Medications:

    • Beta-blockers or calcium channel blockers for symptom management.

    • Anticoagulants for clot risk or atrial fibrillation.

  • Lifestyle: Avoid strenuous activities, especially in symptomatic cases.

  • Devices: Rarely, ICDs for significant arrhythmias.

  • Surgery: Very rare, typically for complications or diagnostic clarity.

Prognosis:

  • Generally good compared to other HCM types.

  • Lower sudden death risk without significant arrhythmias.

  • Requires regular monitoring for heart function and arrhythmias.

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At least for him Rapamycin worked immediately:

“I was in an early stage of heart failure with shortness of breath on walking up hills. After 3 months of weekly rapamycin, I had an excellent clinical response. I continued treatment and by the end of one year, I realized that weekly rapamycin had not only improved my heart condition; but also my prostate symptoms, periodontal gingivitis, overweight and a general feeling of being old. When I hailed my 73 birthday, I felt fabulous. I have now been on continuous treatment for the past 6 years. At age 79, I have no complaints. For a more detailed description see My Story, Section IX.”

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I’m so sad to hear this this news. A big “thank you” to this website and Linda who posted the announcement. Not sure how I would have heard the news otherwise. I was a patient of Dr. Green’s for 5 years. I really enjoyed working with him and I learned so much. My last appointment was on August 16th. He didn’t sound good. I asked him how he was feeling and he told me that it was his cardiomyopathy and he was flying out to the Mayo clinic for treatment. His words to me were “I’m hoping for the best”. I was shocked and I knew it was bad. Something told me to buy him a “thank you” card and pen a personal note, letting him know how much I appreciated him and that I wished him the best. He’ll be missed. What an amazing doctor.

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I was patient number 2 in his practice. He was #1 March 2017. Was living in Boston at the time and flew up to meet him. He gave me an Rx for 600 1 mg. tablets of rapa. He will be missed. Dr. Alan Green - Star of David Memorial Chapels

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A bit optimistic. Dr Green was probably born in 1944? Life expectancy then was 60. I suspect he had other health problems beside his heart disease.

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