Joseph  
            
           
           
          
              
                December 17, 2022,  5:21pm
               
               
          #1 
           
         
        
          Dosing melatonin?
Am going to start using Pierpaoli protocol, increased the dose 3x.
         
         
           
        
            
            
            
         
         
             
             
          
            
       
      
        
        
          Please give a reference link. I am a fan of melatonin, but i tend to take it to extend sleep or just to top up mitochondrial melatonin.
         
         
        
            
            
            
         
         
             
             
          
       
      
        
          
          
            Joseph  
            
           
           
          
              
                December 17, 2022,  6:29pm
               
               
          #3 
           
         
        
          
I did, in the other thread I started.
His web site is;
  
  
    
  In 1967, Walter Pierpaoli proved the relationship between the neuroendocrine system and the immune system.
  
    Est. reading time: 11 minutes 
  
   
  
    
    
  
  
 
         
         
        
            
            
            
         
         
             
             
          
       
      
        
        
          Isn’t that TRH rather than Melatonin.
         
         
        
            
            
            
         
         
             
             
          
       
      
        
        
          I have taken between 0 and 990mg nightly, partially to sleep, but to maintain sleep and extend it rather than initially get to sleep.   Similar other reasons.
         
         
        
            
            
            
         
         
             
             
          
       
      
        
        
          Here are my notes from elsewhere on this site about the use of melatonin supplements:
  
  
    Some notes from the video in the comment above https://youtu.be/YU9QUbsqrcQ : 
Melatonin levels are both an internal clock and an internal calendar, the latter because of the changing amount of light in different seasons. 
You should take Melatonin at the same time very night. 
Avoid blue light at night, and avoid light during the night. 
Retinas have a set of photoreceptors (not cones or rods) that affect the internal clock. 
Fire light, candle light, and moon light have no blue. 
Night lights should be red, yellow, orange. 
Melatonin helps set the biological clock of a developing fetus. Nursing children for 3-4 months and maybe as long as 5-6 months do not produce melatonin – they get it from nursing. Babies who do not nurse do not receive this melatonin. Some have speculate…