Not sure if anyone can clarify. I ask because I’ve read that Rapamycin’s half life means it should pretty much have completely left the body within two to three days, but I can still feel its effects on day seven of cycling it weekly.
So is it permanently bonding to and inactivating my copies of mTOR1 (and some mTOR2)? Meaning that mTOR activity will only upregulate again when new copies of the enzymes are produced? Or is something else going on?