If you have any research papers I have not covered, but are from between years 2022 to today, please post the links to the paper here and I will try to get them and summarize them.
Papers prior to 2022 are usually available for free download from Sci-Hub: https://www.sci-hub.st
Pharmacological modulation of circadian rhythms in brain microvasculature: https://doi.org/10.1177/0271678X251399116
Cognition-enhancing drugs: current landscape, mechanisms, and future prospects: https://www.sciencedirect.com/science/article/abs/pii/S135964462600070X
Lysosomes signal through the epigenome to regulate longevity across generations: https://www.science.org/doi/10.1126/science.adn8754
A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging: https://www.science.org/doi/10.1126/science.adp5056
Longevity steps on the cGAS: https://www.science.org/doi/10.1126/science.aeb6125
Asthma and obstructive sleep apnea: A complex but treatable relationship: https://www.sciencedirect.com/science/article/abs/pii/S1087079225000991
Melatonin’s paradox: From therapeutic benefits to toxicity warnings: https://www.sciencedirect.com/science/article/abs/pii/S0009279725001863
Melatonin: beyond circadian regulation - exploring its diverse physiological roles and therapeutic potential: https://www.sciencedirect.com/science/article/abs/pii/S1087079225000760
The Therapeutic Potential of Melatonin and Its Novel Synthetic Analogs in Circadian Rhythm Sleep Disorders, Inflammation-Associated Pathologies, and Neurodegenerative Diseases: https://onlinelibrary.wiley.com/doi/10.1002/med.22117
Scalp hair repigmentation after radiotherapy: https://academic.oup.com/ced/article-abstract/50/11/2341/8163917
Gray Hair Repigmentation in Androgenetic Alopecia Under Oral Minoxidil: https://onlinelibrary.wiley.com/doi/10.1111/ijd.70431
Antagonistic stem cell fates under stress govern decisions between hair greying and melanoma: https://www.nature.com/articles/s41556-025-01769-9
Hair Repigmentation Outcomes in Patients With Graying Hair Treated With Exosome Therapy: A Cross-Sectional Observational Study: https://onlinelibrary.wiley.com/doi/10.1111/jocd.70526
Ergothioneine regulates the paracrine of dermal papilla cells through SIRT1/Nrf2 pathway to antagonize oxidative stress and natural hair follicle aging: https://www.sciencedirect.com/science/article/abs/pii/S0891584925007257
You’re mean. 
LOL. I felt bad as I furiously typed every possible relevant term into Pubmed. These are all of the latest articles behind paywall that I felt were relevant.
I do apologize.
No problem. No hurry - just add things as you come across things that look interesting and are not accessible. I’m going to keep this forum thread going.
SS-31/Elamipretide studies:
α-Klotho studies:
Exogenous Alpha-Klotho/recombinant human α-Klotho (2022-2026 PAYWALLED):
Combination of α-Klotho and telmisartan attenuates diabetic kidney disease via mitigating EMT, inflammation and apoptosis Combination of α-Klotho and telmisartan attenuates diabetic kidney disease via mitigating EMT, inflammation and apoptosis - PubMed
Emerging role of α-Klotho in energy metabolism and cardiometabolic diseases Emerging role of α-Klotho in energy metabolism and cardiometabolic diseases - PubMed
Alpha-Klotho/α-Klotho (2026 PAYWALLED STUDIES):
α-Klotho as a central integrative signalling hub in cognitive function and neuroprotection in neurodegenerative diseases α-Klotho as a central integrative signalling hub in cognitive function and neuroprotection in neurodegenerative diseases - PubMed
α -Klotho Promotes Cell Death and Suppresses Inflammation through TNF-Cellular Inhibitor of Apoptosis Protein 1 Signaling in Autosomal Dominant Polycystic Kidney Disease α -Klotho Promotes Cell Death and Suppresses Inflammation through TNF-Cellular Inhibitor of Apoptosis Protein 1 Signaling in Autosomal Dominant Polycystic Kidney Disease - PubMed
Endogenous α-Klotho is a common target in atherosclerosis and calcific aortic valve disease Endogenous α-Klotho is a common target in atherosclerosis and calcific aortic valve disease - PubMed
Association between serum alpha Klotho levels and the likelihood of abdominal aortic calcification Association between serum alpha Klotho levels and the likelihood of abdominal aortic calcification - PubMed
Association between serum α-Klotho levels and severity of periodontitis in a representative U.S. population Association between serum α-Klotho levels and severity of periodontitis in a representative U.S. population - PubMed
Alpha-Klotho-deficient female mice exhibit estrogen metabolic dysregulation and a premature ovarian insufficiency-like phenotype Alpha-Klotho-deficient female mice exhibit estrogen metabolic dysregulation and a premature ovarian insufficiency-like phenotype - PubMed
Serum α-Klotho and its association with testosterone in boys with central precocious puberty Serum α-Klotho and its association with testosterone in boys with central precocious puberty - PubMed
Relationship of serum α-Klotho with diabetic kidney disease and mortality in diabetes: A population-based observational study Relationship of serum α-Klotho with diabetic kidney disease and mortality in diabetes: A population-based observational study - PubMed
NEGATIVE EFFECTS OF ELEVATED ALPHA-KLOTHO/α-Klotho?
Association of Klotho with cognitive impairment and sleep difficulties: a multicenter cross-sectional study Checking your browser - reCAPTCHA
Old and new pituitary biomarkers: evidence for sex-specificity Checking your browser - reCAPTCHA
This, while valuable, could be overwhelming. A huge job for you putting it together, and lots of stuff to read for those of us riding your coattails. Maybe each topic could be organized with a short conversational style paragraph to start. That could explain what the intervention is, whether it’s available now, or if not, its likely timeframe and roadblocks (which roadblocks would include potential side effects), and if available now, its accessibility, dosing method and costs. Then,some link or something connecting to your usual AI deeper dive if the paragraph is intriguing enough to draw us in further.
Kind of like you’re doing already, but with more emphasis on getting the basic info out there in a quick read.
A V02Max study that explains how it declines with age.
I’d love to help out! However, we definitely need more people participating in this thread.
New Paywalled paper which should be of interest to all.
Yuting Jessy Tan et al, Restored clearance of senescent neutrophils by tissue-resident macrophages limits organ aging, Science (2026). DOI: 10.1126/science.aea3075. www.science.org/doi/10.1126/science.aea3075
Garret A. FitzGerald, Tidying up aging organs, Science (2026). DOI: 10.1126/science.aei9816