**Sholto David **uncovered yet another antibody cock-up! And again, the main problem is not just scientists using a completely unsuitable antibody, but the beautiful and convincing results they manage to produce nevertheless! And it is not just some Chinese labs, even one of most influential anti-aging researchers in USA is affected!
The antibody kerfuffle now is about β-galactosidase. Apparently the mammalian senescence-associated β-galactosidase and bacterial β-galactosidase are basically the same thing, because scientists have spoken.
I added a Coda about one of these US geniuses, to show you how exactly they manage to achieve perfect figures for publication in top journals without achieving any experimental data.
Here is Sholto’s past reporting about an antibody mix-up, it was about two very unrelated p16 proteins, which will also feature in this post again: