I’m curious what you think about these studies:
Should dill extract be explored as one of potential anti-aging supplements?
I also wonder if other foods/spices/herbs that are more commonly consumed than dill seeds may have comparable or even higher levels of phenols that matter.
That’s what one of the studies says:
“While the mechanism underlying this protective effect remains unclear, it may be
related to the polyphenols, e.g., tannins and flavonoids that are present in dill seeds”
Maybe these are polyphenols available from a varied healthy diet, or are they specific to dill? These are fantastic results on blood pressure and heart hypertrophy in mice.
from the third paper:
While the mechanism underlying this protective effect remains unclear, it may be
related to the polyphenols, e.g., tannins and flavonoids that are present in dill seeds [46,47].
Polyphenols have previously been shown to have beneficial effects on the cardiovascular system
through their antioxidant activity [48–51].
Very interesting! Thank you so very much for sharing! 
Have ordered a dill and blackberry face serum. I also had my first (what I call my ‘heart and face power’) breakfast with a teaspoon of dill seeds added (to a handful of walnuts, goji berry, blend of superfood seeds, high polyphenol extra virgin olive oil, chia seed oil, wheat germ oil and Greek yogurt). I barely tasted the dill so upping to two teaspoons tomorrow.
Also ordered blackberries, which are arriving later and will be in tomorrow’s breakfast
It’s an interesting idea that I have looked into briefly before. Unfortunately there are side effects from increasing LOXL1 and they can be serious so trying to increase it with high doses of dill may have unacceptable risk. Lysyl Oxidase and the Tumor Microenvironment - PubMed
Might be interesting to take along with a copper-Tripeptide subcutaneous injection, which has anti-cancer activity, declines with ageing, and is implicated in collagen synthesis.
Apart from a place to buy, this link collates scientific studies:
It seems to be a mixed bag and honestly, I don’t have enough medical background to evaluate the results of this study. Other articles I have read on dill seed extracts indicate that it may not be good for long-term use. Since dill seeds, powders, extracts, etc. are widely used in the food chain I suspect it is a dose-related problem. For now, at least, I will put up with my aged skin until I know more about dill seed extract.
Here is the full article:
https://sci-hub.se/10.3390/ijms18010062
What i would ask about dill is what the mechanism is. There is IMO no single magic pill for longevity. Molecules affect mechanisms. Which one?
Increased LOXL1 is the mechanism here.
I would like to bump this older thread for more discussion on dill extracts.
I wanted to reproduce some of the experiments. I purchased 20oz of dill seeds and ground it up in my wife’s blender. It irreversibly scored the plastic. I then used a pressure cooker to extract the homogenized tissue. I cooked it for about 60 min under pressure and let it cool overnight. I then used a vino wine filter apparatus and tried to filter but there was still sediment. What a mess.
I was going to order more seeds when I thought maybe I should just order the herbal part instead of the seed. Would it be the same? So I read up on the constituents and realized that there are different kinds of dill, namely Anethum graveolens (European cultivars) and Anethum graveolens var. sowa (East Indian cultivar), and then there’s Peucedanum graveolens, but I don’t think we’re interested in this last kind.
The European and East Indian cultivars are different due to the presence of dillapiole. This is a biologically active compound not present in the European cultivars, at least according to this site.
So if its not the dillapiole, then its a mixture of terpenes? I doubt it.
Another important term/name I discovered is LYS’LASTINE V, which is a dill extract concoction from BASF. Its name came up from this earlier 2006 study LOXL as a target to increase the elastin content in adult skin: a dill extract induces the LOXL gene expression. This is #2 study in the OP.
Seems they use different Anethum graveolens cultivars related to this extract as AI states “For leaf production, which is likely relevant for Lys’Lastine V, cultivars like “Fernleaf” and “Teddy” are popular due to their compact size and slow-bolting characteristics, making them suitable for consistent leaf production”. But AI sucks, tells me dillapiole causes upregulation of elastin and LOXL, which isn’t true if the European dill extracts were used.
This suggests leaf is used instead of dill seed extract, but the papers I’ve read all mention Dill Extracts and their methods say they used Dill Seed, not the foliage.
A recent thesis states “Dill seeds (batch 20958, Leon Cailleau herboristerie, Chemille, France) were grinded with a coffee grinder during 30 seconds and then 5g of this powder were melted in 100mL of distilled water during one night at 4°C. After, this solution was centrifuged 15min at 8000g at 4°C and filtered until 0.22μm and stored at -20°C until further use. The solution obtained was considered at concentration 100%”.
So dill seeds from France again suggests solely European dill, but one never really knows except for the source.
I find there’s a lot of details missing in the information provided. Just using “Dill Seeds” doesn’t cut it. And the extraction method… does cold pressed oil work? does alcohol extraction work? How about steam distillation? Will a simple herbal tea made from the herb do the same?
With all these studies, it can still be difficult to navigate in these unknowns. If anyone knows more about dill extracts, I’d Love to hear about it, as it seems like one of the only compounds that may reverse aortic dilations.
edit: I should also add the number Dill, extract (90028-03-8) as it comes up in the BASF formulation sheet for Lys’Lastine V. Using that # I’m able to find different suppliers, some say Dill Seed extract, but others state Dill Herb extract.