1:1 is too thick for DEP. 1:2 is ideal for elastin production anyway. And no good reason to dilute any further
Yes please!
Hi all, sorry I couldn’t find which DEP device you have been buying, or where you got it from? Can you please share?
I think it’s this:
For some reason I thought this was expensive so wasn’t interested, but now that I see it’s under $200, I’m probably going in…
I’ll wait to make sure this is the correct link
@medaura is that your real name? I ask because you requested we tell them who sent us. You can pm me with a name if you’d like
Also, can you clarify… we ask for David Ma, or was that for another product ?
And, for now, I’m not interest in using things that might give me permanent or a long term filling effect like radiesse, but I was thinking of using this for my existing serums (one has exosomes and rapa, and the other exosomes, stem cells, peptides etc)… just in the hopes of making those more effective. .is my thinking correct?
@Beth Thanks, no it’s not my real name! I can DM you my name. But @LaraPo said she got the third generation device that’s the latest model. I don’t know if David Ma carries that. If the price is not much higher I’d probably go for the latest gen, so maybe check where she bought it. For the legacy model that IS the right link.
I bought the latest model DEP with no syringe attached from Alibaba.com. Put DEP Plus into search, price $175, connected with the first seller and received it 10 days later. It came with a brochure in Chinese and some English - mostly pictures “before and after”. I payed by PayPal.
Ok so I think it’s high time we came to an acknowledgment that the cheap Chinese knockoffs WORK. It’s pretty amazing isn’t it?
I tried it again today with CytoCare 532. Put it on setting 4. Was a little painful in some areas. The result is good on upper face, on cheeks and around eyes where I have fine lines, but deeper lines (lower face, marionette and nasolabial) were not improved. Those require injection for correction. CytoCare 532 gives much better results if applied as mesotherapy - so it was like wasting the whole 5ml without achieving the best result. For that reason I decided not to try diluted Radiesse by DEP - don’t want to waste it. It has to be applied by cannula as designed for the best and lasting result.
DEP as I understand now was most likely designed for younger skin which does not require serious correction. It’s ideal for aestheticians who want their clients to have procedures weekly.
I’m still figuring out what I might use the DEP machine for, and in addition to using it to help serums soak in better, I wondered about hands.
You’ve mentioned possibly using it with radiesse or sculptra. Do you think one of those, or perhaps a filler like juviderm could go in evenly through hands to plumb them up? I would never spend money to have a doc inject my hands, but if this was a simple DIY procedure, not having the hands of a 98 year old would be appealing
Thoughts?
My opinion - it’s wasting of money (for me). I can inject myself and you have to go to a doctor to do that. So what’s wasting of money for me could be a find for you. In other words it’s difficult to advise. The best thing would be to try it at least once. Could you find an aesthetician in your area who has it?
And it will do nothing for your hands. Radiesse or just Juvederm injection will add volume - and it’s a quick and painless procedure that gives immediate results.
That is a clever idea… I will see if anyone in our little tiny town has one and how much it would cost. (They rape and pillage in this area, so one time will most likely cost more than buying the machine!)
I’m not quite ready to pull the trigger (still learning), but if I do, and if you regret buying it, I’d be happy to buy yours vs from a stranger if that helps you out.
I think whoever offers it will charge more for the treatment than the cost of the device. Sculptra is something I haven’t tried but I mean to. Theoretically it’s supposed to be PERFECT for the DEP as it’s very watery.
Can regular ol’ face serums be used, or do we need to use things of a certain molecular weight… and things that are more pure (no preservatives or whatever else would be in otc facial serums).
Also keep in mind that DEP effectiveness depends much on skin age - younger ppl will always have better results. So when somebody half your age tells you that it works wonders for them, take it with a grain of skepticism. We are reaching the age when nothing is going to work. Why do you think Kris Jenner had a deep plane facelift instead of using DEP? ![]()
Serums should not be used because you do not want preservatives and other chemicals pushed into your skin.
I have not seen any information on this. Why do you say this? Why would this be?
It’s just my observation and simple logic. When skin is young it would respond dramatically even to a simple moisturizer. Simple moisturizer would not produce any dramatic results on a 60 - 70 year old face. Skin care recommendations change for different ages.
I don’t see any dramatic results with DEP on my 70 year old face. However @medaura (40?) is very happy with what DEP does for her. The same DEP, but different age categories. DEP works better for her than for me because of the age difference.
I mean those who are over 50-60 shouldn’t expect the same results as much younger ppl.
How Skin Changes with Age
(Copilot search)
• Thinner Epidermis: The outer layer of skin becomes thinner over time, reducing its barrier function and altering how treatments penetrate
• Reduced Collagen & Elastin: Aging skin has diminished collagen and elastin, leading to less firmness and slower repair capacity
• Lower Cellular Turnover: Younger skin renews itself more rapidly, which enhances responsiveness to treatments that rely on regeneration.
• Decreased Vascularization: Blood vessels become more fragile and less efficient with age, reducing nutrient delivery and healing capacity
• Drier Skin: Sebaceous and sweat gland activity declines, making older skin more prone to dryness and less receptive to hydrophilic agents
I don’t know about it being that much less effective with age. Much has to do with WHAT you inject. Did you try dilute radiesse like I did? Did you wait 3-4 weeks like I did to see the end result? Did you repeat the treatment 4-5 times like I did, 4-6 weeks apart? If you do all the things I did as I did them but didn’t get a result worth patting yourself in the back for, then I might be inclined to agree with you that perhaps older skin just doesn’t respond as well.
@Beth you’ll only want to use DEP with solutions which you would have injected otherwise. If it’s safe for an injection it’s safe for DEP. Using it with run of the mill serums and moisturizers meant for topical use will not only not help but quite likely create problems for the reasons LaraPo gave.
It’s not exactly a pleasant experience either so do it with something worth the discomfort. I highly recommend trying Sculptra, dilute Radiesse, and / or any other mesotherapy cocktails / biostimulators, but I think the former two will give you the most bang for the buck. Plan as many vials of Sculptra as decades you are old, 2x that if you want to go heavy, and space them 4-8 weeks apart. It’s a marathon, not a sprint.

