Where do you source Dasatinib? I have mine from Dr. Green but once I run out, am I going to find another source?
cronoslogical, The Dasatinib has never given me a problem either, but the Quercetin does cause some problems which are manageable. I never do D + Q and Rapamycin together. I drop the Rapamycin when doing the D + Q protocol.
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I get mine from an Indian source.
Most of the regular indian vendors we have on our list sell dasatinib.
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Sorry, couldn’t resist. This is one of the longer lists I have seen from the Mayo Clinic.
I tried to take it but couldn’t overcome the side effects, mainly diarrhea. This is not a common side effect of taking dasatinib. I would suggest reading the Mayo Clinic article before proceeding with your polypharma venture. This may be one of those interventions where the risk-reward ratio is unfavorable.
The common side effects are:
More common
Bleeding gums
bloody or black, tarry stools
body aches or pain
burning, tingling, numbness, or pain in the hands, arms, feet, or legs
chest pain or tightness
chills
constipation
cough
coughing up blood
decrease in the amount of urine
dizziness
ear congestion
fainting
fast, slow, or irregular heartbeat
fever
full or bloated feeling
headache
hoarseness
increased menstrual flow or vaginal bleeding
loss of voice
lower back or side pain
noisy or rattling breathing
nosebleeds
painful or difficult urination
pale skin
paralysis
pressure in the stomach
prolonged bleeding from cuts
red or dark brown urine
runny or stuffy nose
sensation of pins and needles
severe stomach pain
sneezing
sore throat
stabbing pain
swelling of the stomach area
swelling of the face, fingers, hands, feet, or lower legs
trouble breathing
ulcers, sores, or white spots in the mouth
unsteadiness or awkwardness
unusual bleeding or bruising
unusual tiredness or weakness
vomiting of blood or material that looks like coffee grounds
weakness in the arms, hands, legs, or feet
weight gain
Less common
Blue lips and fingernails
chest discomfort
coughing that sometimes produces a pink frothy sputum
difficult or fast breathing
dilated neck veins
increased sweating
irregular breathing
loss of appetite
nausea
stomach pain, severe
swelling in the legs and ankles
vomiting
yellow eyes or skin
The end. 
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Could an anti-aging therapy dasatinib + quercetin (D+Q) worsen myelin loss? Findings raise caution and MS clues
A two-drug combination frequently used in anti-aging research causes brain damage in mice, report University of Connecticut researchers in the Proceedings of the National Academy of Sciences. The findings, titled “Senolytic treatment induces oligodendrocyte dysfunction and demyelination in the corpus callosum,” should make doctors cautious about prescribing the drug combo prophylactically, but also suggest new ways to understand multiple sclerosis.
“When you administer this cocktail to an animal, young or old, the myelin is damaged, which makes it disappear. Even worse in the young animals” than in the aged ones, says UConn School of Medicine immunologist Stephen Crocker.
Myelin is the insulation around the nerves. When it disappears, nerves don’t work as well, and people can develop numbness, pain, and lose the ability to walk. They can also have problems thinking and remembering. Missing myelin is the primary cause of multiple sclerosis. Crocker and his colleagues saw it happen to mice when treated with dasatinib+quercetin (D+Q) at doses often used to treat aging-related inflammation and metabolic disorders.
Popular anti-aging combo under scrutiny
D+Q is a popular combination of medicines in anti-aging research. Many studies have shown it works to eliminate aged cells that contribute to inflammation and other age-related symptoms. It is being tested for a range of diseases, from type II diabetes to Alzheimer’s. People in the anti-aging scene sometimes even use it off-label, though the medical community discourages this. Very few studies have looked at its effect on the brain.
Full writeup: https://medicalxpress.com/news/2026-03-anti-aging-therapy-worsen-myelin.html
Research Paper:
Senolytic treatment induces oligodendrocyte dysfunction and demyelination in the corpus callosum, Proceedings of the National Academy of Sciences (2026). DOI: 10.1073/pnas.2524897123
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Well that’s scary. I wonder if the doses they used were relevant to doses used by humans? The full paper is paywalled.